PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18336795-8	2008	[alpha32P]8N3ADP trapping by MRP1-Pro1150Ala could be increased by using Ni2+ instead of Mg2+, and by decreasing temperature; however, the transport properties of the mutant remained unchanged.	magnesium ion	89-93	ATP binding cassette subfamily B member 1	Homo sapiens	29-33	
31774117-5	2019	Our results show that P-gp is significantly thermostabilized (>22 C higher IT50) by the binding of ATP under non-hydrolyzing conditions (in the absence of Mg2+).	magnesium ion	155-159	ATP binding cassette subfamily B member 1	Homo sapiens	22-26	
16803457-3	2006	We studied the trapped complexes formed via incubation of Pgp with ATP (catalytically forward) or ADP (reverse) and V(i), BeF(x) or AlF(x) using Mg2+ or Co2+ as the bivalent cation.	magnesium ion	145-149	ATP binding cassette subfamily B member 1	Homo sapiens	58-61	
10820025-2	2000	In the present study, we explored the nature of Mg(2+)-ATP binding in the N-terminal nucleotide-binding domain of human P-glycoprotein and identified the minimal functional unit required for specific ATP binding.	magnesium ion	48-54	ATP binding cassette subfamily B member 1	Homo sapiens	120-134	
16697012-0	2006	Structure of the human multidrug resistance protein 1 nucleotide binding domain 1 bound to Mg2+/ATP reveals a non-productive catalytic site.	magnesium ion	91-95	ATP binding cassette subfamily B member 1	Homo sapiens	23-53	
16697012-5	2006	Contrary to the prokaryotic NBDs, the extremely low intrinsic ATPase activity of isolated MRP1-NBDs allowed us to obtain the structure of wild-type NBD1 in complex with Mg2+/ATP.	magnesium ion	169-173	ATP binding cassette subfamily B member 1	Homo sapiens	90-94	
9778376-4	1998	Preincubation of human Pgp expressed in Sf9 insect cells with vanadate in the presence of Mg2+, ATP, and verapamil resulted in nearly complete and stable inhibition of the drug-stimulated ATPase function.	magnesium ion	90-94	ATP binding cassette subfamily B member 1	Homo sapiens	23-26	
9778376-8	1998	In support of this conclusion, vanadate, in the presence of Mg2+ and verapamil, caused selective trapping of 8-azido [alpha-32P] ATP and covalent labeling of ATP-binding site in the Pgp.	magnesium ion	60-64	ATP binding cassette subfamily B member 1	Homo sapiens	182-185	
34066059-0	2021	Upregulation of Chemoresistance by Mg2+ Deficiency through Elevation of ATP Binding Cassette Subfamily B Member 1 Expression in Human Lung Adenocarcinoma A549 Cells.	magnesium ion	35-39	ATP binding cassette subfamily B member 1	Homo sapiens	72-113	
7608182-6	1995	Transport was prevented by omission of Mg2+, by substitution of nonhydrolyzable adenylyl-beta,gamma-imidodiphosphate for ATP, by inhibition of the ATPase activity of P-glycoprotein with vanadate and N-ethylmaleimide, and by the chemosensitizers verapamil and amiodarone.	magnesium ion	39-43	ATP binding cassette subfamily B member 1	Homo sapiens	166-180	
7913830-6	1994	While phosphorylation by [gamma-32P]ATP was Mg(2+)-dependent, the enhanced phosphorylation of Pgp by GTP was supported by Mg2+ or Mn2+ and to a lesser extent, Ca2+.	magnesium ion	122-126	ATP binding cassette subfamily B member 1	Homo sapiens	94-97	
9799532-4	1998	Efficient DNA entrapment in preformed liposomes was obtained using the freeze/thawing procedure, and the doxorubicin passive diffusion was quantified in the presence of ATP/Mg2+, the second substrate of P-glycoprotein.	magnesium ion	173-177	ATP binding cassette subfamily B member 1	Homo sapiens	203-217	
9799532-9	1998	Since this cation is essential for P-glycoprotein activity, it can be concluded that in these conditions the accurate evaluation of P-glycoprotein-catalyzed doxorubicin transport will be obtained from the Mg2+-sensitive transport into DNA-loaded proteoliposomes.	magnesium ion	205-209	ATP binding cassette subfamily B member 1	Homo sapiens	35-49	
9799532-9	1998	Since this cation is essential for P-glycoprotein activity, it can be concluded that in these conditions the accurate evaluation of P-glycoprotein-catalyzed doxorubicin transport will be obtained from the Mg2+-sensitive transport into DNA-loaded proteoliposomes.	magnesium ion	205-209	ATP binding cassette subfamily B member 1	Homo sapiens	132-146