PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29649568-0	2018	Honokiol alleviates the degeneration of intervertebral disc via suppressing the activation of TXNIP-NLRP3 inflammasome signal pathway.	honokiol	0-8	NLR family, pyrin domain containing 3	Rattus norvegicus	100-105	
29649568-8	2018	Thus, our results demonstrate that honokiol inhibited the H2O2 induced apoptosis, oxidative stress, and inflammatory responses through the depression of TXNIP/NLRP3/caspase-1/ Interleukin - 1beta signaling axis and the activation of NF-kB and JNK.	honokiol	35-43	NLR family, pyrin domain containing 3	Rattus norvegicus	159-164	
29649568-6	2018	We also found that honokiol suppressed the phosphorylation of NF-kB and JNK, and activation of TXNIP-NLRP3 inflammasome in H2O2-stimulated nucleus pulposus cells, thereby inhibiting the activation of downstream inflammatory mediators such as Interleukin-1beta.	honokiol	19-27	NLR family, pyrin domain containing 3	Rattus norvegicus	101-106