PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33143523-7	2021	In addition, nicotinamide enhanced the RUNX2 protein level and transacting activity posttranslationally with Sirt2 inhibition.	Niacinamide	13-25	sirtuin 2	Mus musculus	109-114	
28478325-2	2017	Here, we established that the nicotinamide adenine dinucleotide-dependent deacetylase sirtuin 2 (SIRT2) interacts with protein kinase B, and, via the glycogen synthase kinase 3beta/beta-catenin pathway, modulates the differentiation of DA neurons.	Niacinamide	30-42	sirtuin 2	Mus musculus	86-95	
28478325-2	2017	Here, we established that the nicotinamide adenine dinucleotide-dependent deacetylase sirtuin 2 (SIRT2) interacts with protein kinase B, and, via the glycogen synthase kinase 3beta/beta-catenin pathway, modulates the differentiation of DA neurons.	Niacinamide	30-42	sirtuin 2	Mus musculus	97-102	
18987186-6	2008	Nicotinamide also dramatically increased acetylated alpha-tubulin, a primary substrate of SirT2, and MAP2c, both of which are linked to increased microtubule stability.	Niacinamide	0-12	sirtuin 2	Mus musculus	90-95	
26620281-7	2015	Deacetylation of GKRP is effected by the NAD(+)-dependent, class III histone deacetylase SIRT2, which is inhibited by nicotinamide.	Niacinamide	118-130	sirtuin 2	Mus musculus	89-94