PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33890260-2	2021	It is caused by a mutation in the SLC12A3 gene leading to a dysfunction of the thiazide-sensitive sodium chloride cotransporter and the magnesium transporters in the distal convoluted tubules.	Magnesium	136-145	solute carrier family 12 member 3	Homo sapiens	34-41	
33585337-7	2021	We also discuss the clinical approach and the specificities of managing this rare hereditary renal tubulopathy.. LEARNING POINTS: Gitelman syndrome is a rare cause of persistent hypokalaemia.A definitive diagnosis is determined by the identification of mutations in the SLC12A3 gene.Management consists of chronic potassium and magnesium supplementation aimed at symptom control.	Magnesium	328-337	solute carrier family 12 member 3	Homo sapiens	270-277	
32292023-5	2020	Genetic analysis demonstrated a novel heterozygous mutation in the SLC12A3 gene; therefore, we diagnosed GS and started potassium and magnesium replacement.	Magnesium	134-143	solute carrier family 12 member 3	Homo sapiens	67-74	
26770037-9	2016	Patients with 2 mutant SLC12A3 alleles, compared with those with 1 mutant allele, did not have more severe clinical and laboratory findings except for lower plasma magnesium concentrations.	Magnesium	164-173	solute carrier family 12 member 3	Homo sapiens	23-30	
28124936-3	2016	Hypomagnesemia is caused by the impairment of magnesium reabsorption through TRPM6 channel which is located just by NCCT.	Magnesium	46-55	solute carrier family 12 member 3	Homo sapiens	116-120	
24645554-2	2013	In this work we systematically analyze molecular mechanisms through which magnesium regulates potassium homeostasis: ATP-sensitive inward rectifier K-channels, Na+/K(+)-ATPases and their regulatory protein SIK1, transporter SLC12A3 and WNK-kinases.	Magnesium	74-83	solute carrier family 12 member 3	Homo sapiens	224-231