PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18056264-0 2008 Specific recognition of Rac2 and Cdc42 by DOCK2 and DOCK9 guanine nucleotide exchange factors. Guanine Nucleotides 58-76 Rac family small GTPase 2 Homo sapiens 24-28 19088377-5 2009 Furthermore, we found a similar novel phenotype in the absence of Vav1, Vav2, and Vav3, which function as guanine nucleotide exchange factors for Rac1 and Rac2. Guanine Nucleotides 106-124 Rac family small GTPase 2 Homo sapiens 155-159 8621595-3 1996 A second protein that interacts with p120Ras-GAP is P190Rac-GAP, which activates the GTPase of guanine nucleotide-binding proteins of the Rho family (including Rac1 and Rac2). Guanine Nucleotides 95-113 Rac family small GTPase 2 Homo sapiens 169-173 9012677-0 1997 Guanine nucleotide binding properties of Rac2 mutant proteins and analysis of the responsiveness to guanine nucleotide dissociation stimulator. Guanine Nucleotides 0-18 Rac family small GTPase 2 Homo sapiens 41-45 9012677-3 1997 We have generated and purified such Rac2 mutants and characterized their guanine nucleotide binding properties in vitro. Guanine Nucleotides 73-91 Rac family small GTPase 2 Homo sapiens 36-40 9012677-7 1997 We show that guanine nucleotide exchange by smgGDS is dependent upon intact switch 1 and switch 2 regions in Rac2. Guanine Nucleotides 13-31 Rac family small GTPase 2 Homo sapiens 109-113 17227822-1 2007 PI 3,4,5-trisphosphate [PI(3,4,5)P3; PIP3]-dependent Rac exchanger 1 (P-Rex1) is a Rac-specific guanine nucleotide exchange factor abundant in neutrophils and myeloid cells. Guanine Nucleotides 96-114 Rac family small GTPase 2 Homo sapiens 53-56 16085653-7 2005 Statin treatment disrupted the interaction of Rac with its negative regulator the Rho guanine nucleotide dissociation inhibitor (RhoGDI), an interaction that is dependent on protein isoprenylation. Guanine Nucleotides 86-104 Rac family small GTPase 2 Homo sapiens 46-49 11278678-6 2001 These results suggest that D57N Rac2 may act in a dominant negative fashion in cells by sequestering endogenous guanine nucleotide exchange factors. Guanine Nucleotides 112-130 Rac family small GTPase 2 Homo sapiens 32-36 8120032-0 1994 Cytosolic guanine nucleotide-binding protein Rac2 operates in vivo as a component of the neutrophil respiratory burst oxidase. Guanine Nucleotides 10-28 Rac family small GTPase 2 Homo sapiens 45-49 1331090-9 1992 Recombinant Rac 2 was shown to bind guanine nucleotides in a Mg(2+)-dependent fashion. Guanine Nucleotides 36-55 Rac family small GTPase 2 Homo sapiens 12-17 2674130-4 1989 rac1 and rac2 possess four of the five conserved functional domains in ras associated with binding and hydrolysis of guanine nucleotides. Guanine Nucleotides 117-136 Rac family small GTPase 2 Homo sapiens 9-13