PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31095630-0 2019 Mice lacking EFA6C/Psd2, a guanine nucleotide exchange factor for Arf6, exhibit lower Purkinje cell synaptic density but normal cerebellar motor functions. Guanine Nucleotides 27-45 ADP-ribosylation factor 6 Mus musculus 66-70 31095630-2 2019 EFA6C, also known as Psd2, is a guanine nucleotide exchange factor for Arf6 that is preferentially expressed in the cerebellar cortex of adult mice, particularly in Purkinje cells. Guanine Nucleotides 32-50 ADP-ribosylation factor 6 Mus musculus 71-75 27241101-2 2016 It is the fourth member of the EFA6 family with guanine nucleotide exchange activity for Arf6, a small guanosine triphosphatase (GTPase) that regulates endosomal trafficking and actin cytoskeleton remodeling. Guanine Nucleotides 48-66 ADP-ribosylation factor 6 Mus musculus 89-93 27330119-9 2016 Furthermore, neurite outgrowth suppressed by ACAP3 knockdown was rescued by expression of a fast cycle mutant of Arf6 that spontaneously exchanges guanine nucleotides on Arf6, but not by that of wild-type, GTP- or GDP-locked mutant Arf6. Guanine Nucleotides 147-166 ADP-ribosylation factor 6 Mus musculus 113-117 27330119-9 2016 Furthermore, neurite outgrowth suppressed by ACAP3 knockdown was rescued by expression of a fast cycle mutant of Arf6 that spontaneously exchanges guanine nucleotides on Arf6, but not by that of wild-type, GTP- or GDP-locked mutant Arf6. Guanine Nucleotides 147-166 ADP-ribosylation factor 6 Mus musculus 170-174 27330119-9 2016 Furthermore, neurite outgrowth suppressed by ACAP3 knockdown was rescued by expression of a fast cycle mutant of Arf6 that spontaneously exchanges guanine nucleotides on Arf6, but not by that of wild-type, GTP- or GDP-locked mutant Arf6. Guanine Nucleotides 147-166 ADP-ribosylation factor 6 Mus musculus 170-174 18323689-0 2008 The EFA6 family: guanine nucleotide exchange factors for ADP ribosylation factor 6 at neuronal synapses. Guanine Nucleotides 17-35 ADP-ribosylation factor 6 Mus musculus 57-82 26884337-2 2016 Here we show that NMDARs control the activity of the small GTPase ADP-ribosylation factor 6 (Arf6) by consecutively recruiting two related brefeldin A-resistant Arf guanine nucleotide exchange factors, BRAG1 and BRAG2, in a GluN2 subunit-dependent manner. Guanine Nucleotides 165-183 ADP-ribosylation factor 6 Mus musculus 66-91 26884337-2 2016 Here we show that NMDARs control the activity of the small GTPase ADP-ribosylation factor 6 (Arf6) by consecutively recruiting two related brefeldin A-resistant Arf guanine nucleotide exchange factors, BRAG1 and BRAG2, in a GluN2 subunit-dependent manner. Guanine Nucleotides 165-183 ADP-ribosylation factor 6 Mus musculus 93-97 34423792-6 2021 Furthermore, pharmacological inhibition of the Arf6 guanine nucleotide exchange factor suppressed asthma-like allergic inflammation in OVA-challenged WT mice. Guanine Nucleotides 52-70 ADP-ribosylation factor 6 Mus musculus 47-51 33310872-1 2021 ADP-ribosylation factor (Arf) family consisting of six family members, Arf1-Arf6, belongs to Ras superfamily and orchestrates vesicle trafficking under the control of guanine nucleotide exchange factors (GEFs) and GTPase-activating proteins. Guanine Nucleotides 167-185 ADP-ribosylation factor 6 Mus musculus 76-80 31607425-3 2019 IQSEC1-3 encode guanine nucleotide exchange factors for the small GTPase ARF6 and their loss affects a variety of actin-dependent cellular processes, including AMPA receptor trafficking at synapses. Guanine Nucleotides 16-34 ADP-ribosylation factor 6 Mus musculus 73-77