PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26241029-11	2015	Taken together, results demonstrated that E2-BSA induced the COX-2 expression and consequent PGE2 and PGF2alpha release in rat OECs.	Dinoprost	102-111	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	61-66	
31247902-3	2019	COX-2 is the key enzyme in eicosanoid metabolism that converts eicosanoids into a number of PGs, including PGD2, PGE2, PGF2alpha, and prostacyclin (PGI2), all of which exert diverse hormone-like effects via autocrine or paracrine mechanisms.	Dinoprost	119-128	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	0-5	
29482802-10	2018	Hence, interaction with COX-2, NPY may affect the levels of PGF2alpha and PGE2 as well as impact the proliferation of granulosa cells in ovaries, thus further reducing the luteal formation, and promoting luteal structural and functional regression, as well as the ovarian steroidogenesis following EA treatment.	Dinoprost	60-69	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	24-29	
21999702-7	2011	COX-2 activity was evaluated with a commercial activity assay kit and by measurement of PGF2alpha production.	Dinoprost	88-97	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	0-5	
19539681-12	2009	These results suggest that PGF2alpha increased the ANP secretion and positive inotropy through PLC-IP3-PKC-MLCK pathway, and the modulation of ANP secretion by COX-2 inhibitor and PGF2alpha may partly relate to the development of renal hypertension.	Dinoprost	27-36	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	160-165	
18707853-0	2008	Danggui-Shaoyao-San, a traditional Chinese prescription, suppresses PGF2alpha production in endometrial epithelial cells by inhibiting COX-2 expression and activity.	Dinoprost	68-77	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	135-140	
9348208-9	1997	Addition of indomethacin (1 microM) and a specific COX-2 inhibitor (NS-398, 1 microM) blocked the OT-induced PGF2alpha production.	Dinoprost	109-118	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	51-56	
9348208-15	1997	Collectively, these results demonstrate, for the first time, that COX-2 is involved in the mechanism by which OT regulates PGF2alpha production in the endometrium.	Dinoprost	123-132	cytochrome c oxidase II, mitochondrial	Rattus norvegicus	66-71