PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29237911-4 2017 SETTINGS AND DESIGN: This study was conducted to determine whether RET dysfunction involves an induced mutation into SK-N-MC cells. sk-n-mc 117-124 ret proto-oncogene Homo sapiens 67-70 29237911-6 2017 SK-N-MC cells with different RET plasmids treated/untreated by GDNF, AKT and ERK1/2 phosphorylation detected by specific antibodies. sk-n-mc 0-7 ret proto-oncogene Homo sapiens 29-32 29237911-8 2017 CONCLUSION: RET dysfunction involves an induced mutation into SK-N-MC cells. sk-n-mc 62-69 ret proto-oncogene Homo sapiens 12-15 26065416-4 2015 Constitutive activation of RET in a SK-N-MC cell line model reduces cell sensitivity to chemotherapy. sk-n-mc 36-43 ret proto-oncogene Homo sapiens 27-30 18751369-0 2008 RET activation inhibits doxorubicin-induced apoptosis in SK-N-MC cells. sk-n-mc 57-64 ret proto-oncogene Homo sapiens 0-3 18751369-2 2008 MATERIALS AND METHODS: Each RET isoform was separately expressed in SK-N-MC cells (neural crest-derived tumor) and the impact of RET activation on doxorubicin-induced apoptosis was examined. sk-n-mc 68-75 ret proto-oncogene Homo sapiens 28-31 18751369-3 2008 RESULTS: The activation of RET9 and RET51 in the SK-N-MC cells significantly reduced the doxorubicin-induced apoptosis by 50%, compared to untreated cells. sk-n-mc 49-56 ret proto-oncogene Homo sapiens 36-41 18751369-6 2008 CONCLUSION: In SK-N-MC cells, downstream activation of MAP kinase, by both RET9 and RET51, appears to mediate the majority of RET-dependent resistance to chemotherapeutically induced apoptosis. sk-n-mc 15-22 ret proto-oncogene Homo sapiens 84-89 18751369-6 2008 CONCLUSION: In SK-N-MC cells, downstream activation of MAP kinase, by both RET9 and RET51, appears to mediate the majority of RET-dependent resistance to chemotherapeutically induced apoptosis. sk-n-mc 15-22 ret proto-oncogene Homo sapiens 75-78 7685595-4 1993 This result was confirmed by using a lysate of SK-N-MC human primitive neuroectodermal tumor cells transfected with the ret proto-oncogene. sk-n-mc 47-54 ret proto-oncogene Homo sapiens 120-123 12056817-2 2002 We found a high level of IL-8 production in SK-N-MC human primitive neuroectodermal tumor cells transfected with the human RET gene (SK-N-MC (RET) cells) in response to glial cell line-derived neurotrophic factor (GDNF) stimulation. sk-n-mc 44-51 ret proto-oncogene Homo sapiens 123-126 12056817-2 2002 We found a high level of IL-8 production in SK-N-MC human primitive neuroectodermal tumor cells transfected with the human RET gene (SK-N-MC (RET) cells) in response to glial cell line-derived neurotrophic factor (GDNF) stimulation. sk-n-mc 44-51 ret proto-oncogene Homo sapiens 142-145 12056817-2 2002 We found a high level of IL-8 production in SK-N-MC human primitive neuroectodermal tumor cells transfected with the human RET gene (SK-N-MC (RET) cells) in response to glial cell line-derived neurotrophic factor (GDNF) stimulation. sk-n-mc 133-140 ret proto-oncogene Homo sapiens 123-126 12056817-2 2002 We found a high level of IL-8 production in SK-N-MC human primitive neuroectodermal tumor cells transfected with the human RET gene (SK-N-MC (RET) cells) in response to glial cell line-derived neurotrophic factor (GDNF) stimulation. sk-n-mc 133-140 ret proto-oncogene Homo sapiens 142-145 12056817-4 2002 To investigate which signaling pathways are responsible for IL-8 expression, we treated SK-N-MC (RET) cells with several kinase inhibitors before GDNF stimulation. sk-n-mc 88-95 ret proto-oncogene Homo sapiens 97-100 11535584-5 2001 Using the neuroectodermic SK-N-MC cell line, we found that the Ret tyrosine kinase activity is essential for GDNF to induce phosphatidylinositol 3-kinase (PI3K)/Akt and ERK pathways as well as cell rescue. sk-n-mc 26-33 ret proto-oncogene Homo sapiens 63-66 9121763-0 1997 Cell scattering of SK-N-MC neuroepithelioma cells in response to Ret and FGF receptor tyrosine kinase activation is correlated with sustained ERK2 activation. sk-n-mc 19-26 ret proto-oncogene Homo sapiens 65-68