PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28218209-10 2017 Inhalation of iloprost resulted in similar changes in mean blood pressure, mPAP, PVR, systemic vascular resistance, CO, arterial oxygen saturation (SaO2), mixed venous oxygen saturation, partial pressure of oxygen in arterial blood (PaO2), PvO2, and intrapulmonary shunt (Qs/Qt) in the PAH and CTEPH groups (all P > 0.05). Iloprost 14-22 phospholipid phosphatase 1 Mus musculus 75-79 11583893-8 2001 Iloprost inhalation significantly decreased mPAP (-9.1 +/- 2.5 mm Hg vs. -7.9 +/- 1.5 mm Hg), PVR (-453 +/- 103 dyne.s.cm(-5) vs. -381 +/- 114 dyne.s.cm(-5)), ANP (-99 +/- 63 pg/ml vs. -108 +/- 47 pg/ml) and cGMP (-4.6 +/- 0.9 nM vs. -4.2 +/- 1.6 nM). Iloprost 0-8 phospholipid phosphatase 1 Mus musculus 44-48 35514784-7 2022 In a comparison of pre-inhalation values at the first and follow-up RHCs, inhaled iloprost significantly improved mean pulmonary artery pressure (mPAP; 39.9 +- 7.8 to 32.5 +- 7.2 mmHg, p = 0.016) and pulmonary vascular resistance (PVR; 588.5 +- 191.7 to 464.4 +- 188.5 dyn s cm-5, p = 0.047). Iloprost 82-90 phospholipid phosphatase 1 Mus musculus 146-150 25992279-8 2015 In summary, nebulized iloprost delivered via the I-neb AAD system reduced mPAP and PVR and increased CI from baseline in a heterogeneous group of patients with PH and in the subset with iPAH. Iloprost 22-30 phospholipid phosphatase 1 Mus musculus 74-78 16242948-7 2005 RESULTS: Iloprost significantly enhanced cardiac index (CI) and reduced mean pulmonary arterial pressure (mPAP) and pulmonary vascular resistance [PVR (dynscm(-5))] in contrast to placebo. Iloprost 9-17 phospholipid phosphatase 1 Mus musculus 106-110 18503929-9 2008 However, in a direct comparison, iloprost caused significantly greater reductions in PVR (p = 0.013) and mPAP (p = 0.0006) and a significantly greater increase in cardiac output (p = 0.002) compared with iNO. Iloprost 33-41 phospholipid phosphatase 1 Mus musculus 105-109 24562636-6 2014 After iloprost inhalation, the patients with low SLEDAI had a greater decrease in mPAP and PVR than those with high SLEDAI, while significantly increased RV systolic function was found only in the low-SLEDAI group. Iloprost 6-14 phospholipid phosphatase 1 Mus musculus 82-86 17804899-12 2008 RESULTS: Significant changes in pulmonary and systemic hemodynamics were observed following the inhalation of iloprost (before to after inhalation): PVR: 1,057 +/- 404.3 to 821.3 +/- 294.3 dyn.s.cm(-5), p < 0.0001; mPAP: 50.55 +/- 8.43 to 45.75 +/- 8.09 mm Hg, p = 0.0002; CO: 3.66 +/- 1.05 to 4.05 +/- 0.91 l/min, p < 0.0106. Iloprost 110-118 phospholipid phosphatase 1 Mus musculus 218-222 12963183-6 2003 Postoperatively, inhaled iloprost induced a significant reduction of mPAP and PVR and a significant increase of CI at T2 and T3. Iloprost 25-33 phospholipid phosphatase 1 Mus musculus 69-73