PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34029971-3 2021 Conjugates were moderate inhibitors of equine and human BChE with negligible fluctuation in anti-BChE activity, whereas anti-AChE activity was substantially dependent on N4-substitution of the piperazine ring. Piperazine 193-203 acetylcholinesterase (Cartwright blood group) Homo sapiens 125-129 32388435-2 2020 Conjugates with piperazine linked to the substituted salicylaldoxime emerged as efficient reactivators for VX inhibited hAChE. Piperazine 16-26 acetylcholinesterase (Cartwright blood group) Homo sapiens 120-125 33743158-0 2021 Piperazine-substituted chalcones: a new class of MAO-B, AChE, and BACE-1 inhibitors for the treatment of neurological disorders. Piperazine 0-10 acetylcholinesterase (Cartwright blood group) Homo sapiens 56-60 24591157-0 2013 Design, synthesis, biological evaluation, and molecular modeling of coumarin-piperazine derivatives as acetylcholinesterase inhibitors. Piperazine 77-87 acetylcholinesterase (Cartwright blood group) Homo sapiens 103-123 30047333-0 2018 2D & 3D-QSAR Study on Novel Piperidine and Piperazine Derivatives as Acetylcholinesterase Enzyme Inhibitors. Piperazine 43-53 acetylcholinesterase (Cartwright blood group) Homo sapiens 69-96 27721153-3 2017 In vitro studies showed that the majority of saccharin derivatives with piperazine moiety and one phthalimide derivative with 3-aminopiperidine fragment exhibited inhibitory potency toward acetylcholinesterase (AChE) with EeAChE IC50 values ranging from 0.83 muM to 19.18 muM. Piperazine 72-82 acetylcholinesterase (Cartwright blood group) Homo sapiens 211-215 24591157-4 2013 Docking experiments of the designed coumarin-piperazine derivatives were carried out in order to compare the theoretical and experimental binding affinities toward hAChE, to delineate the inhibitory mechanism. Piperazine 45-55 acetylcholinesterase (Cartwright blood group) Homo sapiens 164-169 24288651-0 2013 Virtual screening and biological evaluation of piperazine derivatives as human acetylcholinesterase inhibitors. Piperazine 47-57 acetylcholinesterase (Cartwright blood group) Homo sapiens 79-99 24288651-1 2013 The piperazine derivatives have been shown to inhibit human acetylcholinesterase. Piperazine 4-14 acetylcholinesterase (Cartwright blood group) Homo sapiens 60-80