PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8653552-6	1995	Hypothalamic prostaglandin E2 (PGE2) activated by peripheral IL-1 beta, but not peripheral PGE2, increased both activities of HDC and HMT.	Dinoprostone	13-29	histidine decarboxylase	Rattus norvegicus	126-129	
12853415-5	2003	Perfusion of either PGE2 or the EP4 agonist into the TMN at a dose of 200 pmol/min for 1 hr increased histidine decarboxylase activity, histidine decarboxylase mRNA level, and histamine content in the hypothalamus.	Dinoprostone	20-24	histidine decarboxylase	Rattus norvegicus	102-125	
12853415-5	2003	Perfusion of either PGE2 or the EP4 agonist into the TMN at a dose of 200 pmol/min for 1 hr increased histidine decarboxylase activity, histidine decarboxylase mRNA level, and histamine content in the hypothalamus.	Dinoprostone	20-24	histidine decarboxylase	Rattus norvegicus	136-159	
9933502-5	1999	Infusion of prostaglandin E2 (PGE2) into the third cerebroventricle increased the hypothalamic HA turnover rate, and simultaneously activated both HDC and HMT dose-dependently, but intravenous infusion of PGE2 had no effect on the dynamics of hypothalamic HA turnover.	Dinoprostone	12-28	histidine decarboxylase	Rattus norvegicus	147-150	
9933502-5	1999	Infusion of prostaglandin E2 (PGE2) into the third cerebroventricle increased the hypothalamic HA turnover rate, and simultaneously activated both HDC and HMT dose-dependently, but intravenous infusion of PGE2 had no effect on the dynamics of hypothalamic HA turnover.	Dinoprostone	30-34	histidine decarboxylase	Rattus norvegicus	147-150	
9933502-6	1999	These results indicate that hypothalamic PGE2 activated by peripheral administration of IL-1beta, but not by peripheral PGE2, may enhance synthesis and release of hypothalamic HA by activation of HDC, and may facilitate degradation of extracellular histamine by activation of HMT.	Dinoprostone	41-45	histidine decarboxylase	Rattus norvegicus	196-199	
8653552-6	1995	Hypothalamic prostaglandin E2 (PGE2) activated by peripheral IL-1 beta, but not peripheral PGE2, increased both activities of HDC and HMT.	Dinoprostone	31-35	histidine decarboxylase	Rattus norvegicus	126-129