PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 12665526-2 2003 Treatment of cells with the cAMP-elevating agent prostaglandin E(2) (PGE(2)) augmented the level of Cbp/PAG phosphorylation with a concomitant increase in amounts of Csk bound to Cbp/PAG. Dinoprostone 49-67 C-terminal Src kinase Homo sapiens 166-169 12665526-5 2003 Moreover, competition of endogenous Csk from lipid rafts abolished PGE(2)-mediated inhibition of TCR-induced zeta-chain phosphorylation and activation of the nuclear factor of activated T cells (NFAT) activator protein 1 (AP-1). Dinoprostone 67-73 C-terminal Src kinase Homo sapiens 36-39 27038655-6 2016 In the endometriotic lesions, prostaglandin E2 (PGE2) produced by cyclooxygenase-2 (COX-2), binds to its EP4 receptor (EP4), and via c-Src kinase induces MMPs activation, promoting endometriosis. Dinoprostone 30-46 C-terminal Src kinase Homo sapiens 133-145 27038655-6 2016 In the endometriotic lesions, prostaglandin E2 (PGE2) produced by cyclooxygenase-2 (COX-2), binds to its EP4 receptor (EP4), and via c-Src kinase induces MMPs activation, promoting endometriosis. Dinoprostone 48-52 C-terminal Src kinase Homo sapiens 133-145 12665526-2 2003 Treatment of cells with the cAMP-elevating agent prostaglandin E(2) (PGE(2)) augmented the level of Cbp/PAG phosphorylation with a concomitant increase in amounts of Csk bound to Cbp/PAG. Dinoprostone 69-75 C-terminal Src kinase Homo sapiens 166-169 12606547-2 2003 Here, we demonstrate that activation of Csk through a prostaglandin E(2)-cAMP-protein kinase A (PKA) pathway inhibits Src. Dinoprostone 54-72 C-terminal Src kinase Homo sapiens 40-43 12727858-5 2003 Inhibition of C-SRC tyrosine kinase activity also blocks PGE(2)-induced HIF-1alpha protein and VEGF mRNA expression without blocking ERK phosphorylation. Dinoprostone 57-63 C-terminal Src kinase Homo sapiens 14-35