PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22253598-9 2012 Among the known KS-derived immunoregulatory factors, we identified prostaglandin E2 (PGE2) as a critical element responsible for the down-modulation of NKG2D expression on resting NK cells. Dinoprostone 67-83 killer cell lectin like receptor K1 Homo sapiens 152-157 25212604-11 2014 In vitro, suppression of NK cell-mediated lysis and NKG2D expression by ATC cells was restored upon neutralization of prostaglandin-E2. Dinoprostone 118-134 killer cell lectin like receptor K1 Homo sapiens 52-57 22253598-9 2012 Among the known KS-derived immunoregulatory factors, we identified prostaglandin E2 (PGE2) as a critical element responsible for the down-modulation of NKG2D expression on resting NK cells. Dinoprostone 85-89 killer cell lectin like receptor K1 Homo sapiens 152-157 22253598-10 2012 Moreover, PGE2 prevented up-regulation of the NKG2D and NKp30 receptors on IL-15-activated NK cells, and inhibited the IL-15-induced proliferation and survival of NK cells. Dinoprostone 10-14 killer cell lectin like receptor K1 Homo sapiens 46-51