PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31320508-4 2019 Inducible biosynthesis of prostaglandins, including the pro-algesic mediator prostaglandin E2 (PGE2), was decreased in myeloid cells that lack IRE1alpha or XBP1 but not other ER stress sensors. Dinoprostone 77-93 X-box binding protein 1 Homo sapiens 156-160 31320508-4 2019 Inducible biosynthesis of prostaglandins, including the pro-algesic mediator prostaglandin E2 (PGE2), was decreased in myeloid cells that lack IRE1alpha or XBP1 but not other ER stress sensors. Dinoprostone 95-99 X-box binding protein 1 Homo sapiens 156-160 31320508-5 2019 Functional XBP1 transactivated the human PTGS2 and PTGES genes to enable optimal PGE2 production. Dinoprostone 81-85 X-box binding protein 1 Homo sapiens 11-15 26435723-4 2015 By treatment with PGE2, the chondrocytes apoptosis was significantly increased, the proapoptotic CHOP and JNK were upregulated, the prosurvival GRP78 and XBP1 were downregulated, and GSK-3beta was also upregulated. Dinoprostone 18-22 X-box binding protein 1 Homo sapiens 154-158