PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8967374-0	1996	PGE2 and PGI2 inhibit ET-1 secretion from endothelial cells by stimulating particulate guanylate cyclase.	Dinoprostone	0-4	guanylate cyclase	Bos taurus	87-104	
8967374-4	1996	PGE2 and PGI2 each caused a three- to fourfold increase in both membrane and whole bovine aortic endothelial cell guanylate cyclase activity.	Dinoprostone	0-4	guanylate cyclase	Bos taurus	114-131	
8967374-9	1996	We conclude that PGE2 and PGI2 are likely to inhibit ET-1 secretion through the activation of the particulate guanylate cyclase, identifying a novel mechanism by which the prostanoids signal in the endothelial cell.	Dinoprostone	17-21	guanylate cyclase	Bos taurus	110-127