PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1792067-3 1991 However, Lipo-PGE1 dose-dependently decreased the LPS- or CaI A23187-induced production of IL1 and PAF. Alprostadil 14-18 interleukin 1 complex Mus musculus 91-94 7956562-4 1994 (2) PGE1 suppressed the release of tumor necrosis factor (TNF) and secreted-interleukin-1 (SIL-1) in culture supernatants of P.acnes-elicited kupffer cells and membrane IL-1 (mIL-1) in kupffer cells in a dose-dependent manner in vitro. Alprostadil 4-8 interleukin 1 complex Mus musculus 92-96 7956562-4 1994 (2) PGE1 suppressed the release of tumor necrosis factor (TNF) and secreted-interleukin-1 (SIL-1) in culture supernatants of P.acnes-elicited kupffer cells and membrane IL-1 (mIL-1) in kupffer cells in a dose-dependent manner in vitro. Alprostadil 4-8 interleukin 1 complex Mus musculus 175-180 7956562-5 1994 These results strongly suggest that PGE1 can prevent liver cell necrosis in the animal model and the mechanism of curative effect of PGE1 in massive liver cell necrosis may result from inhibition of the activity of TNF, sIL-1 and mIL-1 in the kupffer cells. Alprostadil 36-40 interleukin 1 complex Mus musculus 230-235 7956562-5 1994 These results strongly suggest that PGE1 can prevent liver cell necrosis in the animal model and the mechanism of curative effect of PGE1 in massive liver cell necrosis may result from inhibition of the activity of TNF, sIL-1 and mIL-1 in the kupffer cells. Alprostadil 133-137 interleukin 1 complex Mus musculus 230-235 1792067-4 1991 These results suggested that Lipo-PGE1 acts on hepatic sinusoidal endothelial cells to decrease the production of IL1 and PAF, thereby ameliorating inflammatory reactions in the liver. Alprostadil 34-38 interleukin 1 complex Mus musculus 114-117