PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
1608949-9	1992	Finally, we administered TGF-beta 1 in vivo using an experimental model in which regression of rat liver was initiated by a short preceding treatment with the hepatomitogen cyproterone acetate.	Cyproterone Acetate	173-192	transforming growth factor, beta 1	Rattus norvegicus	25-35	
9163675-0	1997	EGF- and CPA-induced mitogenic stimuli are differentially down-regulated by TGF-beta1 in cultured rat hepatocytes.	Cyproterone Acetate	9-12	transforming growth factor, beta 1	Rattus norvegicus	76-85	
9163675-5	1997	The corresponding down-regulation of CPA-induced PCNA expression required a 3- to 5-fold higher TGF-beta1 concentration than for EGF-induced expression.	Cyproterone Acetate	37-40	transforming growth factor, beta 1	Rattus norvegicus	96-105	
9163675-6	1997	In contrast, CPA-exposed hepatocytes become vulnerable to and EGF-exposed cells protected against the apoptosis-inducing activity of TGF-beta1 (>0.1 ng/ml).	Cyproterone Acetate	13-16	transforming growth factor, beta 1	Rattus norvegicus	133-142	
9163675-8	1997	It is concluded that EGF and CPA induce their growth stimuli preferentially in the periportal area of the liver but in different hepatocyte sub-populations, which differ in their down-regulation of premitotic events by TGF-beta1.	Cyproterone Acetate	29-32	transforming growth factor, beta 1	Rattus norvegicus	219-228	
9163675-9	1997	At low TGF-beta1 concentrations, EGF-stimulated cells shift back into a resting cell cycle phase, whereas CPA-treated hepatocytes are eliminated by apoptosis at higher TGF-beta1 concentrations.	Cyproterone Acetate	106-109	transforming growth factor, beta 1	Rattus norvegicus	168-177