PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7528148-12	1994	Both 15-OH TZP-4238 and cyproterone acetate also reduced the androgen receptor and DHT contents to 50%.	Cyproterone Acetate	24-43	androgen receptor	Rattus norvegicus	61-78	
8331696-7	1993	In the competitive binding assay, procymidone showed a significant but lower binding affinity comparing to that of cyproterone acetate, the steroidal androgen receptor antagonist, for the androgen receptor in both rats and mice under the condition that unlabeled dihydrotestosterone (DHT) effectively inhibited the binding of [3H]-DHT to the androgen receptor in both species.	Cyproterone Acetate	115-134	androgen receptor	Rattus norvegicus	188-205	
10935541-7	2000	Similarly, antiandrogenic ligands, cyproterone acetate and casodex, were also capable of translocating the cytoplasmic AR into the nucleus albeit at a slower rate than the androgen 5alpha-dihydrotestosterone (DHT).	Cyproterone Acetate	35-54	androgen receptor	Rattus norvegicus	119-121	
10935541-8	2000	All AR ligands with transactivation potential, including the mixed agonist/antagonist cyproterone acetate, caused translocation of the GFP-AR into a subnuclear compartment indicated by its punctate intranuclear distribution.	Cyproterone Acetate	86-105	androgen receptor	Rattus norvegicus	4-6	
3758193-3	1986	We determined the short-term and long-term competition of cyproterone acetate and chlormadinone acetate with [3H]DHT for receptor binding at 0 degrees C and showed, that the complexes formed by these antiandrogens with the androgen receptor have equally reduced stabilities compared to the DHT-receptor complex.	Cyproterone Acetate	58-77	androgen receptor	Rattus norvegicus	223-240	
2930988-0	1985	Interactions of an anti-androgen (cyproterone acetate) with the androgen receptor system and its biological action in the rat ventral prostate.	Cyproterone Acetate	34-53	androgen receptor	Rattus norvegicus	64-81	
6227511-0	1983	Cyproterone acetate prevents translocation of the androgen receptor in the rat prostate.	Cyproterone Acetate	0-19	androgen receptor	Rattus norvegicus	50-67	
6227511-1	1983	The translocation of the androgen receptor in prostatic tissue has been studied under the influence of different ligands (testosterone, methyltrienolone and cyproterone acetate) in vivo and in vitro.	Cyproterone Acetate	157-176	androgen receptor	Rattus norvegicus	25-42	
7263637-4	1981	This affinity to the androgen receptor is 1,000-, 500-, 120-, and 40-fold lower than that of 5 alpha-dihydrotestosterone, testosterone, spironolactone, and cyproterone acetate, respectively, and 7-fold higher than that of cimetidine.	Cyproterone Acetate	156-175	androgen receptor	Rattus norvegicus	21-38	
6453438-10	1981	These data suggest that estradiol-17 beta may have a more potent antiandrogenic effect on the epididymis than cyproterone acetate due to inhibition of 5 alpha reduction of testosterone as well as binding to the androgen receptor.	Cyproterone Acetate	110-129	androgen receptor	Rattus norvegicus	211-228	
465307-2	1979	When the androgen-receptor blocking-agent cyproterone acetate was administered together with the testosterone, the subsequent vasopressin treatment did not cause renal cortical necrosis.	Cyproterone Acetate	42-61	androgen receptor	Rattus norvegicus	9-26	
18346198-9	2008	The DHT-mediated increase in NEP expression and decrease in Abeta levels were (i) not observed in rat pheochromocytoma cell 12 lacking AR and (ii) blocked in AR-expressing cells by the antagonists, cyproterone acetate and flutamide.	Cyproterone Acetate	198-217	androgen receptor	Rattus norvegicus	158-160	
12215663-9	2002	CPA caused effects consistent with its mixed AR antagonist/progesterone receptor agonist activity: it decreased ASG weights, caused hormonal alterations (increased T and E2; decreased FSH), and caused spermatid retention.	Cyproterone Acetate	0-3	androgen receptor	Rattus norvegicus	45-47