PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
29093526-0	2017	Spermine oxidase promotes bile canalicular lumen formation through acrolein production.	Acrolein	67-75	spermine oxidase	Homo sapiens	0-16	
16554974-7	2006	It was found that acrolein is mainly produced by spermine oxidase in plasma.	Acrolein	18-26	spermine oxidase	Homo sapiens	49-65	
29093526-1	2017	Spermine oxidase (SMOX) catalyzes oxidation of spermine to generate spermidine, hydrogen peroxide (H2O2) and 3-aminopropanal, which is spontaneously converted to acrolein.	Acrolein	162-170	spermine oxidase	Homo sapiens	0-16	
29093526-1	2017	Spermine oxidase (SMOX) catalyzes oxidation of spermine to generate spermidine, hydrogen peroxide (H2O2) and 3-aminopropanal, which is spontaneously converted to acrolein.	Acrolein	162-170	spermine oxidase	Homo sapiens	18-22	
29093526-11	2017	Our results suggest that SMOX plays a central role in the formation of bile canalicular lumen in liver cells by activating Akt pathway through acrolein production.	Acrolein	143-151	spermine oxidase	Homo sapiens	25-29	
23707493-9	2013	An increase of acrolein by acetaldehyde was SMO dependent.	Acrolein	15-23	spermine oxidase	Homo sapiens	44-47	
24009852-6	2013	Enhanced catabolism of cellular polyamines by polyamine oxidases (PAO), spermine oxidase (SMO) or acetylpolyamine oxidase (AcPAO), increases cellular oxidative stress and generates hydrogen peroxide and a reactive toxic metabolite, acrolein, which covalently incorporates into lysine residues of cellular proteins.	Acrolein	232-240	spermine oxidase	Homo sapiens	72-88	
24009852-6	2013	Enhanced catabolism of cellular polyamines by polyamine oxidases (PAO), spermine oxidase (SMO) or acetylpolyamine oxidase (AcPAO), increases cellular oxidative stress and generates hydrogen peroxide and a reactive toxic metabolite, acrolein, which covalently incorporates into lysine residues of cellular proteins.	Acrolein	232-240	spermine oxidase	Homo sapiens	90-93	
23828398-3	2013	The oxidative products of spermine oxidase activity are spermidine, H2O2 and the aldehyde 3-aminopropanal that spontaneously turns into acrolein.	Acrolein	136-144	spermine oxidase	Homo sapiens	26-42