PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34281282-8	2021	Acrolein suppressed the phosphorylation of glucose metabolic signals IRS1, Akt, mTOR, p70S6K, and GSK3alpha/beta.	Acrolein	0-8	AKT serine/threonine kinase 1	Homo sapiens	75-78	
19596284-7	2009	Exposure to acrolein (<15microM, 30min) activated the survival factor AKT, which led to phosphorylation of Bad and induction of antiapoptosis proteins cIAP1/2.	Acrolein	12-20	AKT serine/threonine kinase 1	Homo sapiens	73-76	
34281282-0	2021	Low-Dose Acrolein, an Endogenous and Exogenous Toxic Molecule, Inhibits Glucose Transport via an Inhibition of Akt-Regulated GLUT4 Signaling in Skeletal Muscle Cells.	Acrolein	9-17	AKT serine/threonine kinase 1	Homo sapiens	111-114	
29093526-11	2017	Our results suggest that SMOX plays a central role in the formation of bile canalicular lumen in liver cells by activating Akt pathway through acrolein production.	Acrolein	143-151	AKT serine/threonine kinase 1	Homo sapiens	123-126	
21951103-7	2012	It was found that acrolein-induced IL-8 production was accompanied by increased levels of phosphorylation of Akt and extracellular signal-regulated kinases (ERK1/2) in HPFs, and that melatonin suppressed IL-8 production in HPFs.	Acrolein	18-26	AKT serine/threonine kinase 1	Homo sapiens	109-112	
21951103-8	2012	These results suggest that melatonin suppresses acrolein-induced IL-8 production via ERK1/2 and phosphatidylinositol 3-kinase (PI3K)/Akt signal inhibition in HPFs.	Acrolein	48-56	AKT serine/threonine kinase 1	Homo sapiens	133-136	
34281282-9	2021	Over-expression of constitutive activation of Akt reversed the inhibitory effects of acrolein on GLUT4 protein expression and glucose uptake in myotubes.	Acrolein	85-93	AKT serine/threonine kinase 1	Homo sapiens	46-49