PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 23305793-10 2013 Acrolein interacted with apolipoprotein B in LDL and Acro-LDL uptake by THP-1 macrophage was a more effective inducer of cholesterol accumulation than oxidized LDL uptake. Acrolein 0-8 apolipoprotein B Homo sapiens 25-41 32919080-2 2021 The purpose of this study was to determine which amino acid residues of apoB protein in LDL are conjugated with acrolein. Acrolein 112-120 apolipoprotein B Homo sapiens 72-76 32919080-3 2021 Acro-apoB was prepared by incubation of LDL with acrolein (10 to 60 muM) at 37 C for 7 days. Acrolein 49-57 apolipoprotein B Homo sapiens 5-9 32919080-4 2021 Identification of acrolein-conjugated amino acid residues in apoB was performed using LC-MS/MS. Acrolein 18-26 apolipoprotein B Homo sapiens 61-65 32919080-5 2021 The levels of acrolein-conjugated amino acid residues of apoB as well as crosslinking apoB increased in proportion to acrolein concentration. Acrolein 14-22 apolipoprotein B Homo sapiens 57-61 32919080-5 2021 The levels of acrolein-conjugated amino acid residues of apoB as well as crosslinking apoB increased in proportion to acrolein concentration. Acrolein 118-126 apolipoprotein B Homo sapiens 57-61 32919080-5 2021 The levels of acrolein-conjugated amino acid residues of apoB as well as crosslinking apoB increased in proportion to acrolein concentration. Acrolein 118-126 apolipoprotein B Homo sapiens 86-90 32919080-6 2021 The level of LDL uptake by macrophages was parallel with the acrolein-conjugated monomer apoB. Acrolein 61-69 apolipoprotein B Homo sapiens 89-93 32919080-7 2021 Acrolein-conjugated amino acid residues in apoB were C212, K327, K742, K949, K1087, H1923, K2634, K3237 and K3846. Acrolein 0-8 apolipoprotein B Homo sapiens 43-47 32919080-9 2021 It is proposed that the rapid uptake of LDL by macrophages is dependent on acrolein conjugation of four amino acids residues at the scavenger receptor recognition site of apoB in LDL. Acrolein 75-83 apolipoprotein B Homo sapiens 171-175