PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20359552-0	2010	Simvastatin attenuates acrolein-induced mucin production in rats: involvement of the Ras/extracellular signal-regulated kinase pathway.	Acrolein	23-31	solute carrier family 13 member 2	Rattus norvegicus	40-45	
20359552-2	2010	Since the small G-protein Ras is known to modulate cellular functions in the lung, we sought to investigate whether the Ras inhibitor simvastatin could attenuate acrolein-induced mucin production in rat airways.	Acrolein	162-170	solute carrier family 13 member 2	Rattus norvegicus	179-184	
20359552-9	2010	In vitro, simvastatin pretreatment attenuated the acrolein-induced significant increase in MUC5AC mucin expression, Ras-GTPase activity and EGFR/ERK phosphorylation.	Acrolein	50-58	solute carrier family 13 member 2	Rattus norvegicus	98-103	
20359552-11	2010	Our results suggest that simvastatin may attenuate acrolein-induced mucin protein synthesis in the airway and airway inflammation, possibly by blocking ERK activation mediated by Ras protein isoprenylation.	Acrolein	51-59	solute carrier family 13 member 2	Rattus norvegicus	68-73	
21036164-0	2011	Doxycycline attenuates acrolein-induced mucin production, in part by inhibiting MMP-9.	Acrolein	23-31	solute carrier family 13 member 2	Rattus norvegicus	40-45	
21036164-2	2011	The aim of this study was to investigate whether doxycycline, a tetracycline antibiotic that inhibits MMPs, attenuates mucus production and synthesis of mucin MUC5AC in acrolein-exposed rats.	Acrolein	169-177	solute carrier family 13 member 2	Rattus norvegicus	153-158	
21036164-7	2011	These results indicate that doxycycline attenuated acrolein-induced mucin synthesis, in part by inhibiting expression of MMP-9.	Acrolein	51-59	solute carrier family 13 member 2	Rattus norvegicus	68-73	
19080078-1	2008	OBJECTIVE: To examine the effects of YM976, a phosphodiesterase (PDE)4 inhibitor, on mucin hypersecretion of airway stimulated with acrolein.	Acrolein	132-140	solute carrier family 13 member 2	Rattus norvegicus	85-90	
19080078-15	2008	CONCLUSION: YM976 inhibits airway inflammatory response and airway mucin hypersecretion induced by acrolein.	Acrolein	99-107	solute carrier family 13 member 2	Rattus norvegicus	67-72