PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26980145-12	2016	Furthermore, the enzyme activity of P450scc, the rate-limiting step of aldosterone synthesis, was elevated after acrolein injection.	Acrolein	113-121	cytochrome P450, family 11, subfamily a, polypeptide 1	Rattus norvegicus	36-43	
26996390-9	2016	Another experiment using trilostane showed less activity of P450scc in zona fasciculata-reticularis (ZFR) cells in acrolein-treated groups.	Acrolein	115-123	cytochrome P450, family 11, subfamily a, polypeptide 1	Rattus norvegicus	60-67	
26996390-14	2016	These results suggested that acrolein decreased the releasing ability of corticosterone via an inhibition on the response of ZFR cells to ACTH and the reduction of protein expressions of StAR and MC2R as well as the activity of P450scc in rat ZFR cells.	Acrolein	29-37	cytochrome P450, family 11, subfamily a, polypeptide 1	Rattus norvegicus	228-235