PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11223428-9 2001 Moreover, high doses (1.0-10 mM) of acrolein and 4-hydroxynonenal, reactive aldehydic species associated with cigarette smoke, completely inhibited plasma LCAT activity, whereas PAF-AH was resistant to such exposures. Acrolein 36-44 lecithin-cholesterol acyltransferase Homo sapiens 155-159 7583533-6 1995 The short-chain (acrolein) and long-chain (HNE) alpha,beta-unsaturated aldehydes were the most effective LCAT inhibitors. Acrolein 17-25 lecithin-cholesterol acyltransferase Homo sapiens 105-109 7473602-7 1995 Among five aldehydes tested, acrolein was the strongest inhibitor of LCAT, with complete enzyme inhibition occurring at 1 mM. Acrolein 29-37 lecithin-cholesterol acyltransferase Homo sapiens 69-73 7473602-10 1995 When plasma was incubated with 1 mM acrolein in the presence of 2.5 mM glutathione or dihydrolipoic acid, 100 and 57% of LCAT activity, respectively, remained after incubation. Acrolein 36-44 lecithin-cholesterol acyltransferase Homo sapiens 121-125