PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34968849-3	2022	In this research, a novel fluorescent probe named "probe for acrolein detection" (Pr-ACR) was designed and synthesized based on a naphthalimide fluorophore skeleton, and a thiol group (-SH) was introduced into its structure for acrolein recognition.	Acrolein	61-69	acrosin	Homo sapiens	85-88	
27036235-1	2016	The acrolein derived cyclic 1,N(2)-propanodeoxyguanosine adduct (Acr-dG), formed primarily from omega-3 polyunsaturated fatty acids such as docosahexaenoic acid (DHA) under oxidative conditions, while proven to be mutagenic, is potentially involved in DHA-induced apoptosis.	Acrolein	4-12	acrosin	Homo sapiens	65-68	
27036235-8	2016	These results clearly demonstrate that NER deficiency induces higher levels of Acr-dG in cells treated with DHA or acrolein and sensitizes cells to undergo apoptosis in a correlative manner.	Acrolein	115-123	acrosin	Homo sapiens	79-82	
19341237-12	2009	The reduced Acr-dG formation is attributed to the reaction of BSA with acrolein as indicated by increased levels of total protein carbonyls.	Acrolein	71-79	acrosin	Homo sapiens	12-15	
19341237-13	2009	Similar correlations between Acr-dG formation and apoptosis were observed in HT-29 cells directly incubated with 0-200 microM acrolein.	Acrolein	126-134	acrosin	Homo sapiens	29-32	
34968849-3	2022	In this research, a novel fluorescent probe named "probe for acrolein detection" (Pr-ACR) was designed and synthesized based on a naphthalimide fluorophore skeleton, and a thiol group (-SH) was introduced into its structure for acrolein recognition.	Acrolein	228-236	acrosin	Homo sapiens	85-88	
34968849-7	2022	After methyl esterification, the methyl esterified probe (mPr-ACR) successfully visualised acrolein in Hela cells under a laser scanning confocal microscope.	Acrolein	91-99	acrosin	Homo sapiens	62-65	
34968849-8	2022	This finding proved that Pr-ACR and mPr-ACR are potential tools for the detection and visualisation of acrolein from different sources.	Acrolein	103-111	acrosin	Homo sapiens	28-31	
34968849-8	2022	This finding proved that Pr-ACR and mPr-ACR are potential tools for the detection and visualisation of acrolein from different sources.	Acrolein	103-111	acrosin	Homo sapiens	40-43	
34131238-9	2021	Furthermore, acrolein-induced DNA damages (Acr-dG adducts) were higher in CRC tumor tissues than in normal epithelial cells in CRC patients.	Acrolein	13-21	acrosin	Homo sapiens	43-46	
29226874-5	2018	We found that the levels of acrolein-conjugated protein (Acr-PC) in the plasma (p = 0.00012) and CSF (p = 0.00161) of AD patients were significantly higher than those of control subjects, whereas the levels of a urinary acrolein metabolite, 3-hydroxypropyl mercapturic acid (3-HPMA), were markedly decreased (p = 0.00882) in AD patients.	Acrolein	28-36	acrosin	Homo sapiens	57-60	
30644728-2	2019	Acrolein reacts directly with DNA to form primarily Acr-dGuo adducts, which serve as important biomarkers for the assessment of exposure to acrolein and its potential role in smoking-related lung cancer.	Acrolein	140-148	acrosin	Homo sapiens	0-3	
29226874-5	2018	We found that the levels of acrolein-conjugated protein (Acr-PC) in the plasma (p = 0.00012) and CSF (p = 0.00161) of AD patients were significantly higher than those of control subjects, whereas the levels of a urinary acrolein metabolite, 3-hydroxypropyl mercapturic acid (3-HPMA), were markedly decreased (p = 0.00882) in AD patients.	Acrolein	220-228	acrosin	Homo sapiens	57-60