PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12604195-12	2003	There was also marked cytotoxic synergism between acrolein and decadienal presumably because of ALDH inactivation by acrolein.	Acrolein	50-58	aldehyde dehydrogenase 3 family, member A1	Rattus norvegicus	96-100	
12604195-12	2003	There was also marked cytotoxic synergism between acrolein and decadienal presumably because of ALDH inactivation by acrolein.	Acrolein	117-125	aldehyde dehydrogenase 3 family, member A1	Rattus norvegicus	96-100	
2795457-6	1989	Collectively, these results indicate that the glutathione-acrolein adduct formed after exposure to acrolein, or as a result of allyl alcohol oxidation and cyclophosphamide metabolism, can be oxidized by hepatic ALDH or ADH, respectively.	Acrolein	58-66	aldehyde dehydrogenase 3 family, member A1	Rattus norvegicus	211-215	
2795457-6	1989	Collectively, these results indicate that the glutathione-acrolein adduct formed after exposure to acrolein, or as a result of allyl alcohol oxidation and cyclophosphamide metabolism, can be oxidized by hepatic ALDH or ADH, respectively.	Acrolein	99-107	aldehyde dehydrogenase 3 family, member A1	Rattus norvegicus	211-215	
2894953-2	1988	Previous investigations into the enzymatic process responsible for the detoxification of acrolein implicated rat liver aldehyde dehydrogenase (ALDH) in the oxidation of this aldehyde.	Acrolein	89-97	aldehyde dehydrogenase 3 family, member A1	Rattus norvegicus	119-141	
2894953-2	1988	Previous investigations into the enzymatic process responsible for the detoxification of acrolein implicated rat liver aldehyde dehydrogenase (ALDH) in the oxidation of this aldehyde.	Acrolein	89-97	aldehyde dehydrogenase 3 family, member A1	Rattus norvegicus	143-147	
2894953-7	1988	The inhibition is rapid with a 91 and 33% reduction in control mitochondrial and cytosolic ALDH activities, respectively, with a 5-sec preincubation of 30 microM acrolein prior to the addition of the aldehyde substrate.	Acrolein	162-170	aldehyde dehydrogenase 3 family, member A1	Rattus norvegicus	91-95	
28807058-10	2017	We measured ALDH activity after exposure to HCY or acrolein and the same with pre-treatment with NAC.	Acrolein	51-59	aldehyde dehydrogenase 3 family, member A1	Rattus norvegicus	12-16	
28807058-14	2017	Less ALDH activity was observed after exposure to HCY or acrolein.	Acrolein	57-65	aldehyde dehydrogenase 3 family, member A1	Rattus norvegicus	5-9	
28807058-16	2017	CONCLUSIONS: Increased ROS generation and decreased ALDH activity confirmed that CY metabolites HCY and acrolein are strongly implicated in cardiotoxicity.	Acrolein	104-112	aldehyde dehydrogenase 3 family, member A1	Rattus norvegicus	52-56	
23220588-9	2013	Inhibiting ALDH or depleting GSH in hepatocytes increased cytotoxicity by about 3-fold in acrolein-treated hepatocytes.	Acrolein	90-98	aldehyde dehydrogenase 3 family, member A1	Rattus norvegicus	11-15