PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
15843039-6	2005	Acrolein induced apoptosis through a decrease in mitochondrial membrane potential, the liberation of cytochrome c, the activation of initiator caspase-9, and the activation of the effector caspase-7.	Acrolein	0-8	caspase 9	Homo sapiens	143-152	
19596284-10	2009	Acrolein (3-27microM, 30-60min) activated early stage processes in the mitochondrial pathway of apoptosis, such as Bax translocation to mitochondria, cytochrome c release, caspase-9 activation, and translocation of apoptosis-inducing factor to the nucleus.	Acrolein	0-8	caspase 9	Homo sapiens	172-181	
33583791-7	2020	Furthermore, treatment with acrolein could markedly increase the levels of reactive oxygen species (ROS) and expression of cleavage of caspase-9 and caspase-3 in H9c2 cardiomyocytes, which were significantly reversed by co-treatment with PEF (100uM).	Acrolein	28-36	caspase 9	Homo sapiens	135-144	
29902662-8	2018	Furthermore, caspase-3 and caspase-9 activation showed that acrolein induced EAhy926 cell apoptosis.	Acrolein	60-68	caspase 9	Homo sapiens	27-36