PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27478470-0 2016 Sulforaphane protects against acrolein-induced oxidative stress and inflammatory responses: modulation of Nrf-2 and COX-2 expression. Acrolein 30-38 mitochondrially encoded cytochrome c oxidase II Homo sapiens 116-121 27478470-8 2016 Acrolein-induced inflammation was observed through upregulation (p < 0.001) of COX-2 and PGE2 levels. Acrolein 0-8 mitochondrially encoded cytochrome c oxidase II Homo sapiens 82-87 27478470-10 2016 Acrolein-induced inflammation was significantly inhibited through suppression of COX-2 (p < 0.001) and PGE2 levels (p < 0.001). Acrolein 0-8 mitochondrially encoded cytochrome c oxidase II Homo sapiens 81-86 24558308-0 2014 Korean Red Ginseng water extract inhibits COX-2 expression by suppressing p38 in acrolein-treated human endothelial cells. Acrolein 81-89 mitochondrially encoded cytochrome c oxidase II Homo sapiens 42-47 24558308-5 2014 Acrolein-induced COX-2 expression was accompanied by increased levels of phosphorylated p38 in HUVECs and KRG inhibited COX-2 expression in HUVECs. Acrolein 0-8 mitochondrially encoded cytochrome c oxidase II Homo sapiens 17-22 24558308-5 2014 Acrolein-induced COX-2 expression was accompanied by increased levels of phosphorylated p38 in HUVECs and KRG inhibited COX-2 expression in HUVECs. Acrolein 0-8 mitochondrially encoded cytochrome c oxidase II Homo sapiens 120-125 24558308-6 2014 These results suggest that KRG suppresses acrolein-induced COX-2 expression via inhibition of the p38 mitogen-activated protein kinase signaling pathway. Acrolein 42-50 mitochondrially encoded cytochrome c oxidase II Homo sapiens 59-64 23953484-9 2013 Acrolein at 5-50 mug/mL increased expression of TNF-alpha and COX-2, as shown by RT-PCR and Western blotting. Acrolein 0-8 mitochondrially encoded cytochrome c oxidase II Homo sapiens 62-67