PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22342303-11 2012 Finally, acrolein, an unsaturated aldehyde present in CSE, caused Src activation. Acrolein 9-17 choreoathetosis/spasticity, episodic (paroxysmal choreoathetosis/spasticity) Homo sapiens 54-57 23981515-10 2013 The concentrations of acrolein, MVK and CPO in the CSE were 3368+-334, 2429+-123 and 392.9+-31.8muM (n=4), respectively, which were higher than the cytotoxic concentrations. Acrolein 22-30 choreoathetosis/spasticity, episodic (paroxysmal choreoathetosis/spasticity) Homo sapiens 51-54 23981515-13 2013 These results show that acrolein and MVK are responsible for the acute cytotoxicity of the CSE through PKC/NOX-dependent and -independent mechanisms, whereas CPO is responsible for the delayed cytotoxicity of the CSE through a PKC/NOX-independent mechanism. Acrolein 24-32 choreoathetosis/spasticity, episodic (paroxysmal choreoathetosis/spasticity) Homo sapiens 91-94