PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26870182-5 2016 GA induced caspase-3, caspase-9 and reactive oxygen species activity, elevated the expression of apoptosis regulator Bcl-2-like protein 4 and reduced the mitochondrial membrane potential in SMMC-7721 cells. Gallium 0-2 caspase 3 Homo sapiens 11-20 34181329-8 2021 In 2D culture model, Caspase 3 expression and apoptosis was increased significantly in cells of GA exposed group compared to the control group. Gallium 96-98 caspase 3 Homo sapiens 21-30 26837170-10 2015 GA promoted activation of Caspase-3, -8, and -9 by TRAIL (P<0.05). Gallium 0-2 caspase 3 Homo sapiens 26-47 16868182-5 2007 In analyzing the function of Hsp90 regarding the cytotoxicity/viability of macrophages, we found that the combination of LPS and GA increases apoptosis, as evidenced by the increased caspase-3 activity and the proportion of nuclear/chromatin condensation. Gallium 129-131 caspase 3 Homo sapiens 183-192 16868182-8 2007 Furthermore, we established the mechanism of GA interference with Hsp90 function for LPS-stimulated macrophages, resulting in increased ROS production and caspase-3 activation, and consequently leading to synergistic enhancement of macrophage apoptosis. Gallium 45-47 caspase 3 Homo sapiens 155-164 30651744-8 2019 GA-13315 triggered remarkable apoptosis in A549 cells at the concentration of 25.6 muM and 32 muM (P < 0.05) and activated caspase-3, - 8 and - 9. Gallium 0-2 caspase 3 Homo sapiens 126-148