PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33977847-0 2021 Computational and experimental insights on the interaction of artemisinin, dihydroartemisinin and chloroquine with SARS-CoV-2 spike protein receptor-binding domain (RBD). artemisinin 62-73 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 126-131 34306988-3 2021 Our in silico approach suggested that unique phytocompounds such as emodin, thymol and carvacrol, and artemisinin could physically bind SARS-CoV-2 spike glycoproteins (6VXX and 6VYB), SARS-CoV-2 B.1.351 South Africa variant of Spike glycoprotein (7NXA), and even with ACE2 and prevent the SARS-CoV-2 binding to the host ACE2, TMPRSS2 and neutrapilin-1 receptors. artemisinin 102-113 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 147-152 32696720-0 2021 Antimalarial-agent artemisinin and derivatives portray more potent binding to Lys353 and Lys31-binding hotspots of SARS-CoV-2 spike protein than hydroxychloroquine: potential repurposing of artenimol for COVID-19. artemisinin 19-30 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 126-131 32696720-5 2021 Artesunate, artemisinin and artenimol, showed two mode of interactions with Lys353 and Lys31 binding hotspots of the Spike protein. artemisinin 12-23 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 117-122 34585460-9 2022 The 50% effective concentration (EC50 ) of artemisinin against SARS-CoV-2 Spike pseudovirus was found greater than 50 muM (EC45 ) in HEK293T cell line whereas the cell viability was 94% of the control (P < 0.01). artemisinin 43-54 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 74-79 34306988-4 2021 Since Chloroquine has been looked as potential therapy against COVID-19, we also compared the binding of chloroquine and artemisinin for its interaction with spike proteins (6VXX, 6VYB) and its variant 7NXA, respectively. artemisinin 121-132 surface glycoprotein Severe acute respiratory syndrome coronavirus 2 158-163