PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22309913-4	2012	The chromones were also found to bind reversibly to MAO-A, but with lower affinities compared to MAO-B.	Chromones	4-13	monoamine oxidase A	Homo sapiens	52-57	
23064123-1	2012	A series of C7-substituted chromone (1-benzopyran-4-one) derivatives were synthesized and evaluated as inhibitors of recombinant human monoamine oxidase (MAO) A and B.	Chromones	27-35	monoamine oxidase A	Homo sapiens	135-166	
23064123-4	2012	While the chromone derivatives also exhibit affinities for MAO-A, with IC(50) values ranging from 0.495 to 8.03 muM, they are selective for the MAO-B isoform.	Chromones	10-18	monoamine oxidase A	Homo sapiens	59-64	
23064123-7	2012	With the aid of modeling studies, potential binding orientations and interactions of selected chromone derivatives in the MAO-A and -B active sites are examined.	Chromones	94-102	monoamine oxidase A	Homo sapiens	122-127	
22309913-6	2012	The results of this study are discussed with reference to possible binding orientations of a selected C6-substituted chromone in the active site cavities of MAO-A and -B.	Chromones	117-125	monoamine oxidase A	Homo sapiens	157-169	
21696156-5	2011	Notably, chromone (19) exhibits an MAO-B IC(50) of 63 nM, greater than 1000-fold selectivity over MAO-A, and behaves as a quasi-reversible inhibitor.	Chromones	9-17	monoamine oxidase A	Homo sapiens	98-103