PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32717131-2	2020	In vitro, CD38-mediated NAADP synthesis requires an acidic pH and a nonphysiological concentration of nicotinic acid (NA).	Niacin	102-116	CD38 molecule	Homo sapiens	10-14	
29632067-3	2018	CD38 is the only enzyme known to catalyze NAADP synthesis from NADP and nicotinic acid.	Niacin	72-86	CD38 molecule	Homo sapiens	0-4	
29632067-9	2018	Supplementing CD38-expressing cells with nicotinic acid substantially increased cellular NAADP levels.	Niacin	41-55	CD38 molecule	Homo sapiens	14-18	
25293882-6	2014	Niacin (vitamin B3) is able to control the excess tryptophan oxidation, correcting tryptophan depletion, and therefore represents an interesting strategy to improve CD4 recovery.We aim to design a crossover proof-of-concept study to assess supplementation with an extended-release form of niacin (Niaspan FCT ) in combination with antiretroviral therapy, compared to antiretroviral therapy alone, on T-cell immune activation as defined by changes in the percentage of CD8+ CD38+ HLA-DR+ T-cells.	Niacin	0-6	CD38 molecule	Homo sapiens	473-477	
18323656-0	2008	Changes in the gene expression of C-myc and CD38 in HL-60 cells during differentiation induced by nicotinic acid-related compounds.	Niacin	98-112	CD38 molecule	Homo sapiens	44-48	
18323656-1	2008	Changes in gene expression levels of c-myc and CD38 were examined during the differentiation of HL-60 cells to granulocytes due to three nicotinic acid-related compounds.	Niacin	137-151	CD38 molecule	Homo sapiens	47-51	
8530456-3	1995	In this study, we show that both the cyclase and CD38 can also catalyze the exchange of the nicotinamide group of NADP+ with nicotine acid (NA).	Niacin	125-138	CD38 molecule	Homo sapiens	49-53	
12951526-0	2003	Expression of CD38 in human promyelocytic leukemia HL-60 cell line during differentiation by niacin-related compounds.	Niacin	93-99	CD38 molecule	Homo sapiens	14-18	
12951526-2	2003	We investigated the expression of CD38, which catalyzes the synthesis of cyclic ADP-ribose, a Ca2+ mobilizer, during differentiation by niacin-related compounds.	Niacin	136-142	CD38 molecule	Homo sapiens	34-38	
8701086-16	1996	Both ADP-ribosyl cyclase and CD38 can catalyze the exchange of the nicotinamide group in NADP+ with nicotinic acid, leading to the formation of another Ca+2 mobilizing metabolite, nicotinic acid dinucleotide phosphate (NAADP).	Niacin	100-114	CD38 molecule	Homo sapiens	29-33