PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15881938-5 2005 The cytotoxic action of the spleen cells of immunized mice on tumor line cells YAC-1 was twice as great as that of spleen cells taken from intact animals and potentiated the cytotoxic action of Cisplatin. Cisplatin 194-203 ADP-ribosyltransferase 1 Mus musculus 79-84 24676941-8 2014 We also found that in cisplatin-treated cells, activated caspase 3 cleaved PARP-1 and the decreased level of PARP-1 in turn decreased the expression of nuclear factor (NF)-kappaB, Cox-2 and increased caspase 3, resulting in the enhanced ability of ART1 to regulate CT26 cell apoptosis. Cisplatin 22-31 ADP-ribosyltransferase 1 Mus musculus 248-252 24676941-9 2014 Our research provides initial sight into the synergistic effect of ART1 and PARP-1 on apoptosis induced by cisplatin in murine colon carcinoma CT26 cells. Cisplatin 107-116 ADP-ribosyltransferase 1 Mus musculus 67-71 24335275-7 2013 RESULTS: ART1 knockdown enhanced the inhibition of cell survival and increased the apoptosis induced by CDDP. Cisplatin 104-108 ADP-ribosyltransferase 1 Mus musculus 9-13 24676941-0 2014 Synergistic effect of arginine-specific ADP-ribosyltransferase 1 and poly(ADP-ribose) polymerase-1 on apoptosis induced by cisplatin in CT26 cells. Cisplatin 123-132 ADP-ribosyltransferase 1 Mus musculus 40-64 24676941-6 2014 The results showed that the apoptosis rate in the ART1-cDNA CT26 cells treated with PARP-1 inhibitor 5-aminoisoquinoline (5-AIQ) and cisplatin increased, when compared with the ART1-cDNA CT26 cells treated with cisplatin only or the untreated ART1-cDNA CT26 cells. Cisplatin 133-142 ADP-ribosyltransferase 1 Mus musculus 50-54 24676941-6 2014 The results showed that the apoptosis rate in the ART1-cDNA CT26 cells treated with PARP-1 inhibitor 5-aminoisoquinoline (5-AIQ) and cisplatin increased, when compared with the ART1-cDNA CT26 cells treated with cisplatin only or the untreated ART1-cDNA CT26 cells. Cisplatin 211-220 ADP-ribosyltransferase 1 Mus musculus 50-54 24676941-7 2014 Further studies have shown that PARP-1 is in the downstream of ART1, and plays a role in ART1-mediated CT26 cell apoptosis through the ROCK1/NF-kappaB/PARP-1 pathway when induced by cisplatin. Cisplatin 182-191 ADP-ribosyltransferase 1 Mus musculus 63-67 24676941-7 2014 Further studies have shown that PARP-1 is in the downstream of ART1, and plays a role in ART1-mediated CT26 cell apoptosis through the ROCK1/NF-kappaB/PARP-1 pathway when induced by cisplatin. Cisplatin 182-191 ADP-ribosyltransferase 1 Mus musculus 89-93 2971467-1 1988 3-Aminobenzamide (3AB) and nicotinamide (NA), inhibitors of adenosine-ribose transferase (ADPRT), potentiated the antitumor activity of cisplatin (DDP) on Ehrlich ascites carcinoma in mice. Cisplatin 136-145 ADP-ribosyltransferase 1 Mus musculus 90-95 2971467-1 1988 3-Aminobenzamide (3AB) and nicotinamide (NA), inhibitors of adenosine-ribose transferase (ADPRT), potentiated the antitumor activity of cisplatin (DDP) on Ehrlich ascites carcinoma in mice. Cisplatin 147-150 ADP-ribosyltransferase 1 Mus musculus 90-95 3940633-3 1986 injections of CDDP (2-6 mg/kg) into adult mice significantly enhanced cytolysis of YAC-1 and K562 targets mediated by peritoneal and spleen cells. Cisplatin 14-18 ADP-ribosyltransferase 1 Mus musculus 83-88