PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34358523-0	2021	Integrin alpha5 mediates intrinsic cisplatin resistance in three-dimensional nasopharyngeal carcinoma spheroids via the inhibition of phosphorylated ERK /caspase-3 induced apoptosis.	Cisplatin	35-44	integrin subunit alpha 5	Homo sapiens	0-15	
34358523-4	2021	Thus, the aim of this study was to investigate the effect of integrin alpha5 on the development of intrinsic cisplatin resistance in NPC and the mechanisms responsible using in vitro three-dimensional (3D) spheroid models, as well as induced cisplatin-resistant NPC (NPCcisR).	Cisplatin	109-118	integrin subunit alpha 5	Homo sapiens	61-76	
34358523-10	2021	The results showed dramatic reduction in integrin alpha5 expression, reversal of ERK phosphorylation and caspase-3 cleavage, together with elevated cisplatin sensitivity, indicating regulation of innate drug resistance via integrin alpha5.	Cisplatin	148-157	integrin subunit alpha 5	Homo sapiens	223-238	
31911861-0	2019	Integrin alpha5 promotes migration and cisplatin resistance in esophageal squamous cell carcinoma cells.	Cisplatin	39-48	integrin subunit alpha 5	Homo sapiens	0-15	
31911861-4	2019	Furthermore, we found that the integrin alpha5 expression is remarkably upregulated in Res cells, and inhibition of alpha5 results in more apoptosis and endows the Res cells resensitize to cisplatin in vitro and in vivo.	Cisplatin	189-198	integrin subunit alpha 5	Homo sapiens	31-46