PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30295336-6 2019 In addition, cisplatin experiments with cell counting kit-8, colony formation, and a xenograft mice model of NPC demonstrated that NEK2 contributed to proliferation and cisplatin resistance in vitro and in vivo. Cisplatin 13-22 NIMA (never in mitosis gene a)-related expressed kinase 2 Mus musculus 131-135 30295336-6 2019 In addition, cisplatin experiments with cell counting kit-8, colony formation, and a xenograft mice model of NPC demonstrated that NEK2 contributed to proliferation and cisplatin resistance in vitro and in vivo. Cisplatin 169-178 NIMA (never in mitosis gene a)-related expressed kinase 2 Mus musculus 131-135 30295336-7 2019 On the contrary, downregulation of NEK2 by short hairpin RNA inhibited NPC cell growth and increased the sensitivity of cisplatin treatment in vitro. Cisplatin 120-129 NIMA (never in mitosis gene a)-related expressed kinase 2 Mus musculus 35-39 30295336-9 2019 Targeting NEK2 has the potential to eradicate the cisplatin-based chemotherapy resistant NPC cells. Cisplatin 50-59 NIMA (never in mitosis gene a)-related expressed kinase 2 Mus musculus 10-14 20345485-9 2010 Furthermore, the combined administration of both Nek2 siRNA and CDDP suppressed tumor growth compared to either the single administration of Nek2 siRNA or the combined administration of control siRNA and CDDP. Cisplatin 204-208 NIMA (never in mitosis gene a)-related expressed kinase 2 Mus musculus 49-53