PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29581579-0 2018 Restoration of E-cadherin by PPBICA protects against cisplatin-induced acute kidney injury by attenuating inflammation and programmed cell death. Cisplatin 53-62 cadherin 1 Mus musculus 15-25 31043583-0 2019 3-deazaneplanocin A protects against cisplatin-induced renal tubular cell apoptosis and acute kidney injury by restoration of E-cadherin expression. Cisplatin 37-46 cadherin 1 Mus musculus 126-136 31043583-9 2019 Overall, these data indicate that 3-DZNeP suppresses cisplatin-induced tubular epithelial cell apoptosis and acute kidney injury via an E-cadherin-dependent mechanism, and suggest that combined application of 3-DZNeP with cisplatin would be a novel chemotherapeutic strategy that enhances the anti-tumor effect of cisplatin and reduces its nephrotoxicity. Cisplatin 53-62 cadherin 1 Mus musculus 136-146 29581579-4 2018 Here, we evaluated cell damage and inflammation in cisplatin-stimulated tubular epithelial cell lines after disrupting E-cadherin and restoring it with PPBICA, a small molecule identified by high-throughput screening. Cisplatin 51-60 cadherin 1 Mus musculus 119-129 29581579-6 2018 Results show cisplatin reduced E-cadherin expression both in mouse kidney and proximal tubular epithelial cell lines (mTECs). Cisplatin 13-22 cadherin 1 Mus musculus 31-41 29581579-13 2018 This was driven by restoration of E-cadherin in cisplatin nephropathy. Cisplatin 48-57 cadherin 1 Mus musculus 34-44 23537295-6 2013 In addition, immunohistochemical studies on mouse tumors injected with cisplatin or paclitaxel treated residual cells displayed higher staining for the proliferative antigen Ki67, oncogeneic CA125, epithelial E-cadherin as well as cancer stem cell markers such as Oct4 and CD117, compared to mice injected with control untreated cells. Cisplatin 71-80 cadherin 1 Mus musculus 209-219 27262076-0 2016 Experiment research of cisplatin implants inhibiting transplantation tumor growth and regulating the expression of KLK7 and E-cad of tumor-bearing mice with gastric cancer. Cisplatin 23-32 cadherin 1 Mus musculus 124-129 27262076-7 2016 CONCLUSION: Cisplatin implants can inhibit the growth of transplanted tumor tissue and down-regulated KLK7 expression and up-regulated E-cad expression of tumor-bearing mice with gastric cancer. Cisplatin 12-21 cadherin 1 Mus musculus 135-140