PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32379984-0 2020 miR-205 Promotes Apoptosis of Cervical Cancer Cells and Enhances Drug Sensitivity of Cisplatin by Inhibiting YAP1. Cisplatin 85-94 microRNA 205 Homo sapiens 0-7 32379984-3 2020 In this study, we aim to explore the role of miR-205 in the proliferation, apoptosis, or cisplatin (CDDP) resistance of cervical cancer cells. Cisplatin 89-98 microRNA 205 Homo sapiens 45-52 32379984-3 2020 In this study, we aim to explore the role of miR-205 in the proliferation, apoptosis, or cisplatin (CDDP) resistance of cervical cancer cells. Cisplatin 100-104 microRNA 205 Homo sapiens 45-52 32379984-10 2020 Conclusions: The expression of miR-205 is related to the CDDP resistance of cervical cancer cells. Cisplatin 57-61 microRNA 205 Homo sapiens 31-38 32379984-11 2020 Increasing the expression of miR-205 can downregulate the expression of YAP1, inhibit the proliferation and promote apoptosis of cervical cancer cells, and enhance the sensitivity to CDDP. Cisplatin 183-187 microRNA 205 Homo sapiens 29-36 32277654-12 2020 Additionally, miR-205 enhanced the chemosensitivity of the nasopharyngeal carcinoma cells to cisplatin and suppressed their migration and invasiveness. Cisplatin 93-102 microRNA 205 Homo sapiens 14-21 30510566-0 2018 miR-205-5p Mediated Downregulation of PTEN Contributes to Cisplatin Resistance in C13K Human Ovarian Cancer Cells. Cisplatin 58-67 microRNA 205 Homo sapiens 0-7 31158447-0 2019 miR-205-5p regulates epithelial-mesenchymal transition by targeting PTEN via PI3K/AKT signaling pathway in cisplatin-resistant nasopharyngeal carcinoma cells. Cisplatin 107-116 microRNA 205 Homo sapiens 0-7 31158447-5 2019 In this study, we manifested firstly that the expression of miR-205-5p in cisplatin-resistant NPC cell line HNE1/DDP was obviously up-regulated than that in its parental cell line HNE1. Cisplatin 74-83 microRNA 205 Homo sapiens 60-67 30510566-3 2018 Herein, we found that miR-205-5p was enormously increased in cisplatin-resistant C13K ovarian cancer cells compared with its cisplatin-sensitive OV2008 parental cells using miRNA microarrays, which was further verified by quantitative PCR. Cisplatin 61-70 microRNA 205 Homo sapiens 22-29 30510566-3 2018 Herein, we found that miR-205-5p was enormously increased in cisplatin-resistant C13K ovarian cancer cells compared with its cisplatin-sensitive OV2008 parental cells using miRNA microarrays, which was further verified by quantitative PCR. Cisplatin 125-134 microRNA 205 Homo sapiens 22-29 30510566-4 2018 Furthermore, we confirmed that inhibition of miR-205-5p upregulated PTEN and subsequently attenuated its downstream target p-AKT, which inversed C13K cells from cisplatin resistance to sensitivity. Cisplatin 161-170 microRNA 205 Homo sapiens 45-52 30510566-5 2018 Our data suggest that miR-205-5p contributes to cisplatin resistance in C13K ovarian cancer cells may via targeting PTEN/AKT pathway. Cisplatin 48-57 microRNA 205 Homo sapiens 22-29 29424887-0 2018 MiR-205 enhances cisplatin sensitivity of glioma cells by targeting E2F1. Cisplatin 17-26 microRNA 205 Homo sapiens 0-7 30066866-0 2018 Ultrasound-targeted microbubble destruction-mediated miR-205 enhances cisplatin cytotoxicity in prostate cancer cells. Cisplatin 70-79 microRNA 205 Homo sapiens 53-60 30066866-8 2018 The results of the present study demonstrated that miR-205 expression was low in human PCa cell lines compared with healthy cells and that UTMD-mediated miR-205 delivery inhibited PCa cell proliferation, migration and invasion, and promoted apoptosis modulated by cisplatin compared with UTMD-mediated miR-negative control group and miR-205-treated group. Cisplatin 264-273 microRNA 205 Homo sapiens 153-160 30066866-8 2018 The results of the present study demonstrated that miR-205 expression was low in human PCa cell lines compared with healthy cells and that UTMD-mediated miR-205 delivery inhibited PCa cell proliferation, migration and invasion, and promoted apoptosis modulated by cisplatin compared with UTMD-mediated miR-negative control group and miR-205-treated group. Cisplatin 264-273 microRNA 205 Homo sapiens 153-160 29424887-3 2018 The current research aimed to decipher the role of miR-205 in the development of cisplatin resistance in glioma cells. Cisplatin 81-90 microRNA 205 Homo sapiens 51-58 29424887-4 2018 MATERIALS AND METHODS: miR-205 expressions in both cisplatin sensitive and resistant cell lines were compared by the Real-time PCR method. Cisplatin 51-60 microRNA 205 Homo sapiens 23-30 24370341-0 2014 miR-205 impairs the autophagic flux and enhances cisplatin cytotoxicity in castration-resistant prostate cancer cells. Cisplatin 49-58 microRNA 205 Homo sapiens 0-7 29424887-8 2018 RESULTS: miR-205 expression was decreased in cisplatin resistant glioma cell lines, and cisplatin treatment led to a decrease of miR-205 in glioma cells. Cisplatin 45-54 microRNA 205 Homo sapiens 9-16 29424887-8 2018 RESULTS: miR-205 expression was decreased in cisplatin resistant glioma cell lines, and cisplatin treatment led to a decrease of miR-205 in glioma cells. Cisplatin 88-97 microRNA 205 Homo sapiens 129-136 29424887-9 2018 Overexpression of miR-205 in U87/DDP restored its cisplatin sensitivity by enhancing apoptosis and G1/S cell cycle arrest; notably, all these effects were then partially abrogated by E2F1 overexpression. Cisplatin 50-59 microRNA 205 Homo sapiens 18-25 29424887-11 2018 CONCLUSIONS: These findings suggest that down-regulation of miR-205 confers the cisplatin resistance in glioma cells via upregulation of E2F1. Cisplatin 80-89 microRNA 205 Homo sapiens 60-67 24370341-3 2014 In the present study, we show that miR-205 replacement in castration-resistant mesenchymal prostate cancer cells caused an enhancement of cisplatin cytotoxic activity in vitro and in vivo, as a consequence of autophagy impairment. Cisplatin 138-147 microRNA 205 Homo sapiens 35-42 24370341-5 2014 These findings suggest that miR-205-mediated impairment of the autophagic pathway may interfere with the detoxifying capabilities of prostate cancer cells in their attempt to cope with cisplatin-induced detrimental effects. Cisplatin 185-194 microRNA 205 Homo sapiens 28-35 34520676-0 2021 Retraction of: miR-205 Promotes Apoptosis of Cervical Cancer Cells and Enhances Drug Sensitivity of Cisplatin by Inhibiting YAP1 (doi: 10.1089/cbr.2019.2983). Cisplatin 100-109 microRNA 205 Homo sapiens 15-22 23612742-7 2013 Consistent with its anti-apoptotic target BCL2, miR-205 promoted apoptosis in prostate cancer cells in response to DNA damage by cisplatin and doxorubicin in the prostate cancer cell lines PC3 and LnCap. Cisplatin 129-138 microRNA 205 Homo sapiens 48-55 34322490-5 2021 Downregulation of miR-205 could attenuate HOTTIP-silencing effects whereas miR-205 upregulation in resistant cells was found to re-sensitize cells to cisplatin. Cisplatin 150-159 microRNA 205 Homo sapiens 75-82 34322490-7 2021 Finally, ZEB2 was identified as the gene target of miR-205, thus completing the elucidation of HOTTIP-miR-205-ZEB2 as the novel axis which is functionally involved in the determination of cisplatin resistance in ovarian cancer cells. Cisplatin 188-197 microRNA 205 Homo sapiens 51-58 34322490-7 2021 Finally, ZEB2 was identified as the gene target of miR-205, thus completing the elucidation of HOTTIP-miR-205-ZEB2 as the novel axis which is functionally involved in the determination of cisplatin resistance in ovarian cancer cells. Cisplatin 188-197 microRNA 205 Homo sapiens 102-109