PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31017720-2 2019 We explored the roles and mechanisms of miR-144 in resistance to cisplatin (CDDP) of cervical cancer cells. Cisplatin 65-74 microRNA 144 Homo sapiens 40-47 31017720-0 2019 miR-144 reverses cisplatin resistance in cervical cancer via targeting LHX2. Cisplatin 17-26 microRNA 144 Homo sapiens 0-7 34311128-9 2021 Furthermore, OIP5-AS1 was identified as a sponge of miR-144-5p, and upregulation of miR-144-5p could significantly reverse overexpression of OIP5-AS1-induced protective effect on the damage of cisplatin to HK-2 cells. Cisplatin 193-202 microRNA 144 Homo sapiens 52-59 34311128-9 2021 Furthermore, OIP5-AS1 was identified as a sponge of miR-144-5p, and upregulation of miR-144-5p could significantly reverse overexpression of OIP5-AS1-induced protective effect on the damage of cisplatin to HK-2 cells. Cisplatin 193-202 microRNA 144 Homo sapiens 84-91 34311128-10 2021 In addition, pyruvate kinase M2 (PKM2) was found to be a direct target of miR-144-5p, and overexpression of PKM2 efficiently reversed the effect of miR-144-5p mimics on the damage in cisplatin-stimulated HK-2 cells. Cisplatin 183-192 microRNA 144 Homo sapiens 74-81 34311128-10 2021 In addition, pyruvate kinase M2 (PKM2) was found to be a direct target of miR-144-5p, and overexpression of PKM2 efficiently reversed the effect of miR-144-5p mimics on the damage in cisplatin-stimulated HK-2 cells. Cisplatin 183-192 microRNA 144 Homo sapiens 148-155 31017720-2 2019 We explored the roles and mechanisms of miR-144 in resistance to cisplatin (CDDP) of cervical cancer cells. Cisplatin 76-80 microRNA 144 Homo sapiens 40-47 31017720-3 2019 miR-144 and LIM homeobox 2 (LHX2) expression in CDDP-resistant and the parental cells was determined by quantitative real-time polymerase chain reaction (qRT-PCR) and Western blot analysis, respectively. Cisplatin 48-52 microRNA 144 Homo sapiens 0-7 31017720-5 2019 Overexpression of miR-144 reduced cell viability, induced cell apoptosis, and inhibited cell migration and invasion after CDDP treatment. Cisplatin 122-126 microRNA 144 Homo sapiens 18-25 31017720-9 2019 Taken together, miR-144 overcomes resistance to CDDP via promoting cell apoptosis and inhibiting invasion through targeting LHX2 in cervical cancer cells. Cisplatin 48-52 microRNA 144 Homo sapiens 16-23 31357838-1 2019 Objective: To investigate the effects and mechanisms of miR-144 on proliferation, apoptosis and cisplatin (DDP) resistance of neuroblastoma cells. Cisplatin 107-110 microRNA 144 Homo sapiens 56-63 30542710-0 2018 miR-144-3p regulates the resistance of lung cancer to cisplatin by targeting Nrf2. Cisplatin 54-63 microRNA 144 Homo sapiens 0-7 31357838-0 2019 [Effects of miR-144 on proliferation, apoptosis and cisplatin resistance by targeting MYCN in pediatric neuroblastoma]. Cisplatin 52-61 microRNA 144 Homo sapiens 12-19 31357838-1 2019 Objective: To investigate the effects and mechanisms of miR-144 on proliferation, apoptosis and cisplatin (DDP) resistance of neuroblastoma cells. Cisplatin 96-105 microRNA 144 Homo sapiens 56-63 30542710-3 2018 In the course of the study, we unexpectedly found that miR-144-3p could regulate the cisplatin resistance of lung cancer cells via Nrf2. Cisplatin 85-94 microRNA 144 Homo sapiens 55-62 30542710-6 2018 In addition, we also found that in other cancer cell lines, such as HepG2, miR-144-3p also had the function of regulating cisplatin resistance. Cisplatin 122-131 microRNA 144 Homo sapiens 75-82 26566625-0 2015 VEGF-activated miR-144 regulates autophagic survival of prostate cancer cells against Cisplatin. Cisplatin 86-95 microRNA 144 Homo sapiens 15-22 29504819-0 2018 Effects of miR-144 on the sensitivity of human anaplastic thyroid carcinoma cells to cisplatin by autophagy regulation. Cisplatin 85-94 microRNA 144 Homo sapiens 11-18 29504819-1 2018 BACKGROUND: We investigated the influence of miR-144 on the cisplatin-sensitivity of anaplastic thyroid carcinoma (ATC) cells and explored the internal molecular mechanism of miR-144. Cisplatin 60-69 microRNA 144 Homo sapiens 45-52 29504819-9 2018 RESULTS: MiR-144, which was low expressed in ATC cells and tissues, could inhibit autophagy activation induced by cisplatin, enhancing the sensitivity of ATC cells to cisplatin, and promoting cell apoptosis. Cisplatin 114-123 microRNA 144 Homo sapiens 9-16 29504819-9 2018 RESULTS: MiR-144, which was low expressed in ATC cells and tissues, could inhibit autophagy activation induced by cisplatin, enhancing the sensitivity of ATC cells to cisplatin, and promoting cell apoptosis. Cisplatin 167-176 microRNA 144 Homo sapiens 9-16 29504819-11 2018 MiR-144 could improve the sensitivity of ATC cells to cisplatin and inhibit tumor growth by suppressing TGF-alpha both in vitro and in vivo. Cisplatin 54-63 microRNA 144 Homo sapiens 0-7 29504819-12 2018 CONCLUSION: MiR-144 could inhibit autophagy of ATC cells by down-regulating TGF-alpha, enhancing the cisplatin-sensitivity of ATC cells. Cisplatin 101-110 microRNA 144 Homo sapiens 12-19 26566625-9 2015 Upregulation of miR-144 or suppression of cell autophagy may improve the outcome of cisplatin therapy in PC. Cisplatin 84-93 microRNA 144 Homo sapiens 16-23 26566625-5 2015 Moreover, microRNA (miR)-144 levels were significantly downregulated in cisplatin-treated PC cells, in a VEGF-dependent manner. Cisplatin 72-81 microRNA 144 Homo sapiens 10-28 26566625-7 2015 In PC patients after cisplatin treatment, low miR-144 levels appeared to predict poor outcome of patients" survival. Cisplatin 21-30 microRNA 144 Homo sapiens 46-53 26566625-8 2015 Together, these data suggest that cisplatin may induce VEGF to suppress miR-144 levels in PC cells, which subsequently upregulates Beclin-1 to increase autophagic cell survival against cisplatin-induced cell death. Cisplatin 34-43 microRNA 144 Homo sapiens 72-79