PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32781203-0 2020 Tissue-based long non-coding RNAs "PVT1, TUG1 and MEG3" signature predicts Cisplatin resistance in ovarian Cancer. Cisplatin 75-84 taurine up-regulated 1 Homo sapiens 41-45 32781203-5 2020 CONCLUSION: The lnc-PVT1, lnc-TUG1, and lnc-MEG3 transcriptome signatures could be used for predicting resistance to Cisplatin in OC patients. Cisplatin 117-126 taurine up-regulated 1 Homo sapiens 30-34 32390763-0 2020 TUG1/miR-133b/CXCR4 axis regulates cisplatin resistance in human tongue squamous cell carcinoma. Cisplatin 35-44 taurine up-regulated 1 Homo sapiens 0-4 32390763-10 2020 Results: TUG1 expression was elevated in cisplatin-resistant TSCC tissues and cells compared with that in sensitive group and its knockdown inhibited cisplatin resistance to SCC25/CDDP and CAL27/CDDP cells. Cisplatin 41-50 taurine up-regulated 1 Homo sapiens 9-13 32390763-10 2020 Results: TUG1 expression was elevated in cisplatin-resistant TSCC tissues and cells compared with that in sensitive group and its knockdown inhibited cisplatin resistance to SCC25/CDDP and CAL27/CDDP cells. Cisplatin 150-159 taurine up-regulated 1 Homo sapiens 9-13 32390763-10 2020 Results: TUG1 expression was elevated in cisplatin-resistant TSCC tissues and cells compared with that in sensitive group and its knockdown inhibited cisplatin resistance to SCC25/CDDP and CAL27/CDDP cells. Cisplatin 180-184 taurine up-regulated 1 Homo sapiens 9-13 32390763-10 2020 Results: TUG1 expression was elevated in cisplatin-resistant TSCC tissues and cells compared with that in sensitive group and its knockdown inhibited cisplatin resistance to SCC25/CDDP and CAL27/CDDP cells. Cisplatin 195-199 taurine up-regulated 1 Homo sapiens 9-13 32390763-11 2020 miR-133b was targeted via TUG1 and its overexpression suppressed cisplatin resistance. Cisplatin 65-74 taurine up-regulated 1 Homo sapiens 26-30 32390763-16 2020 Conclusion: Downregulation of TUG1 impeded cisplatin resistance in TSCC-resistant cells by mediating miR-133b and CXCR4, indicating TUG1 as a promising target for TSCC chemotherapy. Cisplatin 43-52 taurine up-regulated 1 Homo sapiens 30-34 30925453-0 2019 lncRNA TUG1 Promotes Cisplatin Resistance by Regulating CCND2 via Epigenetically Silencing miR-194-5p in Bladder Cancer. Cisplatin 21-30 taurine up-regulated 1 Homo sapiens 7-11 31305159-0 2020 Anticancer potential of TUG1 knockdown in cisplatin-resistant osteosarcoma through inhibition of MET/Akt signalling. Cisplatin 42-51 taurine up-regulated 1 Homo sapiens 24-28 31532756-4 2019 TUG1 overexpression was shown to inhibit cell proliferation, migration, invasion, but facilitate apoptosis and autophagy in NSCLC cells resistant to cisplatin (DDP). Cisplatin 149-158 taurine up-regulated 1 Homo sapiens 0-4 31287493-0 2019 LncRNA TUG1 promotes cisplatin resistance in esophageal squamous cell carcinoma cells by regulating Nrf2. Cisplatin 21-30 taurine up-regulated 1 Homo sapiens 7-11 31287493-5 2019 In this study, we showed that TUG1 expression in TE-1-derived cisplatin (DDP)-resistant (TE-1/DDP) cells was higher than that in TE-1 cells. Cisplatin 62-71 taurine up-regulated 1 Homo sapiens 30-34 30925453-5 2019 Increased miR-194-5p expression or decreased TUG1 expression significantly sensitized bladder cancer cells to cisplatin, inhibited the proliferation, and induced apoptosis. Cisplatin 110-119 taurine up-regulated 1 Homo sapiens 45-49 30925453-7 2019 CCND2 could partially restore the tumor-suppressive effects on cell proliferation and cisplatin resistance following TUG1 silencing. Cisplatin 86-95 taurine up-regulated 1 Homo sapiens 117-121 31424656-0 2019 Low expression of TUG1 promotes cisplatin sensitivity in cervical cancer by activating the MAPK pathway. Cisplatin 32-41 taurine up-regulated 1 Homo sapiens 18-22 31424656-1 2019 PURPOSE: This study aims to investigate whether TUG1 can regulate cisplatin resistance in the disease progression of cervical cancer (CC) by activating the MAPK pathway. Cisplatin 66-75 taurine up-regulated 1 Homo sapiens 48-52 31424656-12 2019 TUG1 knockdown inhibited the proliferative rate but accelerated the apoptosis of DDP-induced CC cells. Cisplatin 81-84 taurine up-regulated 1 Homo sapiens 0-4 30098551-0 2018 Long non-coding RNA TUG1 sponges miR-197 to enhance cisplatin sensitivity in triple negative breast cancer. Cisplatin 52-61 taurine up-regulated 1 Homo sapiens 20-24 30519392-0 2018 TUG1 confers cisplatin resistance in esophageal squamous cell carcinoma by epigenetically suppressing PDCD4 expression via EZH2. Cisplatin 13-22 taurine up-regulated 1 Homo sapiens 0-4 30519392-3 2018 In the present study, we investigate the functional role of TUG1 in cisplatin (DDP) resistance of ESCC and discover the underlying molecular mechanism. Cisplatin 68-77 taurine up-regulated 1 Homo sapiens 60-64 30098551-6 2018 In MDA-MB-231 and BT549, cisplatin induced cell growth arrest was remarkably augmented by overexpression of TUG1 and was significantly reduced by TUG1 silencing. Cisplatin 25-34 taurine up-regulated 1 Homo sapiens 108-112 30098551-6 2018 In MDA-MB-231 and BT549, cisplatin induced cell growth arrest was remarkably augmented by overexpression of TUG1 and was significantly reduced by TUG1 silencing. Cisplatin 25-34 taurine up-regulated 1 Homo sapiens 146-150 30098551-7 2018 Moreover, very low concentration of cisplatin caused cell proliferation inhibition in TUG1-overexpressed-TNBC cells. Cisplatin 36-45 taurine up-regulated 1 Homo sapiens 86-90 29543785-14 2018 Inhibition of TUG1 reduced the growth of tumors in vivo and improved the chemosensitivity of A375 cells to cisplatin and 5-FU. Cisplatin 107-116 taurine up-regulated 1 Homo sapiens 14-18