PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
30867794-4	2019	Supporting the in vivo data, immunohistochemical staining of tumor masses from mice treated with AvidinOX, bCet and cisplatin exhibited the highest tumor cell damage and the lowest angiogenic activity among all treatment groups, measured as the number of gamma-H2A.X and cleaved caspase-3-positive cells, and vascular endothelial growth factor-C and platelet and endothelial cell adhesion molecule 1-positive cells, respectively.	Cisplatin	116-125	H2A.X variant histone	Mus musculus	255-266	
26019260-7	2015	Here we show that cisplatin induces germ cell damage through inhibition of p53-dependent DNA repair mechanisms involving gamma-H2AX and ataxia telangiectasia mutated protein kinase.	Cisplatin	18-27	H2A.X variant histone	Mus musculus	121-180	
28057599-8	2017	The in vivo effects of aspirin plus sorafenib on cisplatin therapy were also confirmed in resistant HNC xenograft models, in terms of growth inhibition, GSH depletion, and increased gammaH2AX formation and apoptosis in tumors.	Cisplatin	49-58	H2A.X variant histone	Mus musculus	182-191	
21593482-5	2011	UV irradiation or cisplatin treatment of 2-cell embryos in the G(2) phase of the cell cycle caused DNA damage as defined by increased phosphorylation of the H2A histone family, member X (H2AFX; previously H2AX) variant.	Cisplatin	18-27	H2A.X variant histone	Mus musculus	157-185	
23784839-8	2013	Finally, exposure of spermatocytes to double strand break DNA-damaging agents such as cisplatin, bleomycin or etoposide also induced ATR relocalization and intense H2AX phosphorylation and led to anomalies in synaptonemal assembly.	Cisplatin	86-95	H2A.X variant histone	Mus musculus	164-168	
25387467-7	2014	When comparing cisplatin and PIFA-treated tumours with cisplatin alone treated tumours we found overall less gammaH2AX, a measure for DNA damage.	Cisplatin	15-24	H2A.X variant histone	Mus musculus	109-118	
25387467-7	2014	When comparing cisplatin and PIFA-treated tumours with cisplatin alone treated tumours we found overall less gammaH2AX, a measure for DNA damage.	Cisplatin	55-64	H2A.X variant histone	Mus musculus	109-118	
24571982-6	2014	Interestingly, the gamma-H2AX signal was localized to telomeres after treatment with bleomycin, cisplatin, and 4OOH-CPA, but not etoposide.	Cisplatin	96-105	H2A.X variant histone	Mus musculus	19-29	
21593482-5	2011	UV irradiation or cisplatin treatment of 2-cell embryos in the G(2) phase of the cell cycle caused DNA damage as defined by increased phosphorylation of the H2A histone family, member X (H2AFX; previously H2AX) variant.	Cisplatin	18-27	H2A.X variant histone	Mus musculus	187-192	
21593482-5	2011	UV irradiation or cisplatin treatment of 2-cell embryos in the G(2) phase of the cell cycle caused DNA damage as defined by increased phosphorylation of the H2A histone family, member X (H2AFX; previously H2AX) variant.	Cisplatin	18-27	H2A.X variant histone	Mus musculus	205-209	
19738461-3	2009	The cytotoxicity of cisplatin and beta-lap alone or in combination against FSaII fibrosarcoma cells of C3H mice in vitro was determined with a clonogenic survival assay and assessment of gamma-H2AX foci formation, a hallmark of DNA double-strand breaks.	Cisplatin	20-29	H2A.X variant histone	Mus musculus	187-197	
18927497-5	2008	MEFs lacking Puralpha also showed enhanced H2AX phosphorylation in response to cisplatin.	Cisplatin	79-88	H2A.X variant histone	Mus musculus	43-47	
18162465-6	2008	We show that ATR is specifically activated during cisplatin treatment and co-localizes with H2AX, forming nuclear foci at the site of DNA damage.	Cisplatin	50-59	H2A.X variant histone	Mus musculus	92-96	
33168727-5	2020	Moreover, although p-gamma-H2AX foci formation was elevated and ATR expression was low in single agent cisplatin-treated cells, the opposite was true in cells treated with cisplatin/JH-RE-06.	Cisplatin	172-181	H2A.X variant histone	Mus musculus	21-31