PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 15923181-12 2005 Since phorbol ester enhanced cyclin D1 expression and subsequent G1-to-S-phase transition of endothelial cells, we suggest that the PKC-mediated exclusion of LIMK2 from the nucleus might be a mechanism to relieve suppression of cyclin D1 expression by LIMK2. Phorbol Esters 6-19 cyclin D1 Homo sapiens 29-38 14757441-5 2004 Furthermore, when HL-60 myeloid leukemic cells were differentiated with phorbol ester (TPA), PBK/TOPK protein expression was strongly down-regulated by 24 h. Under these same conditions, phosphorylated c-Myc was rapidly down-regulated (by 4 h), while the levels of cyclin D1 and phosphorylated p38 were constant. Phorbol Esters 72-85 cyclin D1 Homo sapiens 265-274