PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7693872-6	1993	In contrast, increased synthesis of proenkephalin in response to phorbol esters was not affected by pertussis toxin treatment.	Phorbol Esters	65-79	proenkephalin	Bos taurus	36-49	
8632147-1	1996	In bovine chromaffin cells forskolin, phorbol ester, or high potassium levels induce a rapid increase of c-fos, c-jun, and junB mRNA levels, which precede an induction of proenkephalin gene expression.	Phorbol Esters	38-51	proenkephalin	Bos taurus	171-184	
1850068-0	1991	Coordinate and differential regulation of proenkephalin A and PNMT mRNA expression in cultured bovine adrenal chromaffin cells: responses to cAMP elevation and phorbol esters.	Phorbol Esters	160-174	proenkephalin	Bos taurus	42-57	
1850068-1	1991	The expression of proenkephalin A (ProEnk A) mRNA and phenylethanolamine N-methyltransferase (PNMT) mRNA in response to cAMP analogues, forskolin and phorbol esters was examined in cultures of bovine adrenal chromaffin cells.	Phorbol Esters	150-164	proenkephalin	Bos taurus	18-33	
1850068-1	1991	The expression of proenkephalin A (ProEnk A) mRNA and phenylethanolamine N-methyltransferase (PNMT) mRNA in response to cAMP analogues, forskolin and phorbol esters was examined in cultures of bovine adrenal chromaffin cells.	Phorbol Esters	150-164	proenkephalin	Bos taurus	35-43	
1850068-3	1991	Cells exposed to the tumor promoting phorbol esters (phorbol 12-myristate 13-acetate, phorbol 12,13-dibutyrate or 4-beta-phorbol 12,13-didecanoate) for 12 h differentially activated PNMT mRNA and ProEnk A mRNA expression.	Phorbol Esters	37-51	proenkephalin	Bos taurus	196-204	
1850068-7	1991	By contrast, the expression of ProEnk A mRNA was activated by the tumor promoting phorbol esters in a concentration-dependent manner.	Phorbol Esters	82-96	proenkephalin	Bos taurus	31-39	
2448301-2	1988	The increase in phorbol ester-induced proenkephalin mRNA was potentiated by low concentrations of the Ca2+ ionophore A23187, suggesting an interaction between protein kinase- and Ca2+-mediated processes in the regulation of proenkephalin mRNA.	Phorbol Esters	16-29	proenkephalin	Bos taurus	38-51	
2448301-2	1988	The increase in phorbol ester-induced proenkephalin mRNA was potentiated by low concentrations of the Ca2+ ionophore A23187, suggesting an interaction between protein kinase- and Ca2+-mediated processes in the regulation of proenkephalin mRNA.	Phorbol Esters	16-29	proenkephalin	Bos taurus	224-237