PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 9511724-8 1998 Long-term treatment with either the phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA) or bryostatin 1 inhibited levels of Dsg1 and Dsg3, but not Dsg2 in NHEKs and HaCaT cells. Phorbol Esters 36-49 desmoglein 1 Homo sapiens 129-133 2037585-9 1991 Down-regulation of protein kinase C (PKC) by long term treatment with phorbol ester, prior to BK stimulation, resulted in (i) enhanced DGi and decreased PAi formation, suggesting that DG kinase activity is positively controlled by PKC; (ii) the unexpected manifestation of rapidly formed DGc; (iii) no change in the DGc levels obtained after 30-min BK stimulation, but complete suppression of PMA-induced DGc formation. Phorbol Esters 70-83 desmoglein 1 Homo sapiens 135-138