PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30060118-0 2018 The FoxM1-ABCC4 axis mediates carboplatin resistance in human retinoblastoma Y-79 cells. Carboplatin 30-41 forkhead box M1 Homo sapiens 4-9 30060118-4 2018 In this study, we investigated the regulatory effect of FoxM1 on carboplatin resistance in human RB Y-79 cells and carboplatin-resistant Y-79 (Y-79CR) cells, as well as the possible mechanism. Carboplatin 65-76 forkhead box M1 Homo sapiens 56-61 30060118-5 2018 Our results showed that FoxM1 was up-regulated in Y-79CR cells and silencing of FoxM1 promoted carboplatin sensitivity and accumulation, while overexpression of FoxM1 in Y-79 cells performed oppositely. Carboplatin 95-106 forkhead box M1 Homo sapiens 24-29 30060118-5 2018 Our results showed that FoxM1 was up-regulated in Y-79CR cells and silencing of FoxM1 promoted carboplatin sensitivity and accumulation, while overexpression of FoxM1 in Y-79 cells performed oppositely. Carboplatin 95-106 forkhead box M1 Homo sapiens 80-85 30060118-5 2018 Our results showed that FoxM1 was up-regulated in Y-79CR cells and silencing of FoxM1 promoted carboplatin sensitivity and accumulation, while overexpression of FoxM1 in Y-79 cells performed oppositely. Carboplatin 95-106 forkhead box M1 Homo sapiens 80-85 30060118-6 2018 Our study further revealed that FoxM1 enhanced carboplatin resistance in Y-79CR cells through directly up-regulating the transcription of ATP-binding cassette transporter C4 (ABCC4), an important drug efflux transporter. Carboplatin 47-58 forkhead box M1 Homo sapiens 32-37 30060118-7 2018 Overall, our study demonstrated the novel role of FoxM1-ABCC4 axis in human RB, which provides insights into the prevention of carboplatin resistance in human RB. Carboplatin 127-138 forkhead box M1 Homo sapiens 50-55 25426548-0 2014 Targeting of mutant p53-induced FoxM1 with thiostrepton induces cytotoxicity and enhances carboplatin sensitivity in cancer cells. Carboplatin 90-101 forkhead box M1 Homo sapiens 32-37