PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 1953749-1 1991 The early enzyme-mediated reaction sequence in the biosynthesis of melanin from L-tyrosine involves an initial hydroxylation (monophenol oxidase activity, MPO) of the aromatic amino acid precursor to form L-dopa (3,4-dihydroxyphenylalanine), and the ensuing oxidation (diphenol oxidase activity, DPO) of the resultant diphenol to form dopaquinone. dopaquinone 335-346 Prophenoloxidase 1 Drosophila melanogaster 126-144