PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
3098884-1	1986	Skin tyrosinase activity increases during hair growth in C3H-HeAvy mice and reaches higher levels in young (30- to 35-day-old) mice when the hair follicular melanocytes synthesize the black pigment, eumelanin, than in older (6-month-old) mice when they produce the golden yellow pigment, phaeomelanin.	phaeomelanin	288-300	tyrosinase	Mus musculus	5-15	
7548229-0	1995	Fibroblasts co-expressing tyrosinase and the b-protein synthesize both eumelanin and phaeomelanin.	phaeomelanin	85-97	tyrosinase	Mus musculus	26-36	
7548229-8	1995	Only phaeomelanin is detectable in fibroblasts expressing tyrosinase alone, whereas double transfectants synthesise significantly more phaeomelanin and detectable eumelanin.	phaeomelanin	5-17	tyrosinase	Mus musculus	58-68	
8326247-9	1993	It was concluded that, through its actions on the enzyme tyrosinase, alpha-MSH is able to switch the synthesis of phaeomelanin to that of eumelanin in hair follicular melanocytes.	phaeomelanin	114-126	tyrosinase	Mus musculus	57-67	
8505373-0	1993	Fibroblasts expressing mouse c locus tyrosinase produce an authentic enzyme and synthesize phaeomelanin.	phaeomelanin	91-103	tyrosinase	Mus musculus	37-47	
1667073-0	1991	Regulation of tyrosinase in hair follicular melanocytes of the mouse during the synthesis of eumelanin and phaeomelanin.	phaeomelanin	107-119	tyrosinase	Mus musculus	14-24	
1667073-4	1991	However, tyrosinase synthesis and mRNA levels were the same in follicles during eumelanin and phaeomelanin synthesis.	phaeomelanin	94-106	tyrosinase	Mus musculus	9-19	
2502579-11	1989	Although 8-bromo-cAMP increased glycosylation of tyrosinase in both eumelanin and phaeomelanin producing melanocytes, it failed to alter the subcellular distribution of the enzyme.	phaeomelanin	82-94	tyrosinase	Mus musculus	49-59	
3119767-1	1987	Tyrosinase activity at the time of phaeomelanin synthesis in neonatal mice is lower in agouti than in black skin and hair bulb tissue, and this depressed activity is associated with a reduction in the electrophoretically distinct de novo form of the enzyme.	phaeomelanin	35-47	tyrosinase	Mus musculus	0-10	
3084696-4	1986	These results suggest that the changes in coat colour in C3H-HeA*vy mice are due mainly to changes in eumelanin synthesis by the hair follicular melanocytes and that the production of this pigment requires higher levels of the enzyme tyrosinase than does the production of phaeomelanin.	phaeomelanin	273-285	tyrosinase	Mus musculus	234-244