PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22289577-7	2012	The HA22T-implanted nude mice model further confirmed that diosmin inhibited HA22T tumor cell growth and down regulated the PI3K-Akt-MDM2 signaling and cell cycle regulating proteins, as well as activating PP2A and p53 proteins.	Diosmin	59-66	tumor protein p53	Homo sapiens	215-218	
22289577-5	2012	Diosmin showed strong HA22T cell viability inhibition in a dose dependent manner and significantly reduced the cell proliferative proteins as well as inducing cell cycle arrest in the G2/M phase through p53 activation and PI3K-Akt-MDM2 signaling pathway inhibition.	Diosmin	0-7	tumor protein p53	Homo sapiens	203-206	
27890807-0	2017	Diosmin-induced senescence, apoptosis and autophagy in breast cancer cells of different p53 status and ERK activity.	Diosmin	0-7	tumor protein p53	Homo sapiens	88-91	
27890807-4	2017	Diosmin caused G2/M cell cycle arrest, elevation in p53, p21 and p27 levels and stress-induced premature senescence when used at lower concentrations (5 and 10muM).	Diosmin	0-7	tumor protein p53	Homo sapiens	52-55