PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
17159770-6	2006	Moreover, synthetic beta-naphthoflavone and naturally occurring chrysin, quercetin and diosmin induced CYP1A1 in both tissues.	Diosmin	87-94	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	103-109	
9661887-0	1998	Diosmin and diosmetin are agonists of the aryl hydrocarbon receptor that differentially affect cytochrome P450 1A1 activity.	Diosmin	0-7	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	95-114	
9661887-5	1998	Treatment of the cells with diosmin or diosmetin, on the other hand, caused a dose- and time-dependent increase in CYP1A1 activity in intact cells that was comparable to that induced by DMBA or by the aryl hydrocarbon benzo(a)pyrene.	Diosmin	28-35	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	115-121	
9661887-6	1998	Both diosmin and diosmetin caused an increase in the transcription of the CYP1A1 gene, as measured by increased levels of CYP1A1 mRNA.	Diosmin	5-12	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	74-80	
9661887-6	1998	Both diosmin and diosmetin caused an increase in the transcription of the CYP1A1 gene, as measured by increased levels of CYP1A1 mRNA.	Diosmin	5-12	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	122-128	
9661887-8	1998	These results indicate that diosmin and diosmetin are natural dietary agonists of the AhR, causing a potent increase in CYP1A1 transcription and CYP1A1 activity; however, only diosmetin is capable of inhibiting CYP1A1 enzyme activity, thus inhibiting carcinogen activation.	Diosmin	28-35	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	120-126	
9661887-8	1998	These results indicate that diosmin and diosmetin are natural dietary agonists of the AhR, causing a potent increase in CYP1A1 transcription and CYP1A1 activity; however, only diosmetin is capable of inhibiting CYP1A1 enzyme activity, thus inhibiting carcinogen activation.	Diosmin	28-35	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	145-151	
9661887-8	1998	These results indicate that diosmin and diosmetin are natural dietary agonists of the AhR, causing a potent increase in CYP1A1 transcription and CYP1A1 activity; however, only diosmetin is capable of inhibiting CYP1A1 enzyme activity, thus inhibiting carcinogen activation.	Diosmin	28-35	cytochrome P450 family 1 subfamily A member 1	Homo sapiens	145-151