PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
32512072-9	2020	Treatment with diosmin demonstrated multiple beneficial effects as it significantly ameliorated histopathological NASH findings, lowered TNF-alpha, interleukin-6, and malondialdehyde levels, improved lipid and glucose metabolism, and lowered hepatic TGF-beta, alpha-SMA, and collagen content compared to untreated rats.	Diosmin	15-22	interleukin 6	Rattus norvegicus	148-161	
31902439-8	2020	Also, diosmin treatment significantly (P < 0.05) lowered the levels of interleukin-1beta (IL-1beta), interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha), down-regulated cardiac Bcl-2-associated X protein and caspase 3 and 9 and up-regulated B-cell lymphoma 2 mRNA expression levels.	Diosmin	6-13	interleukin 6	Rattus norvegicus	104-117	
31902439-8	2020	Also, diosmin treatment significantly (P < 0.05) lowered the levels of interleukin-1beta (IL-1beta), interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha), down-regulated cardiac Bcl-2-associated X protein and caspase 3 and 9 and up-regulated B-cell lymphoma 2 mRNA expression levels.	Diosmin	6-13	interleukin 6	Rattus norvegicus	119-123	
29091880-11	2018	The anti-hyperalgesic effects of diosmin were also linked with reduced levels of TNF-alpha, IL-1beta and IL-6.	Diosmin	33-40	interleukin 6	Rattus norvegicus	105-109	
31797688-7	2020	Further, immunohistochemical study showed that diosmin alleviated inflammatory markers (nuclear factor kappa-light-chain-enhancer of activated B cells, cyclooxygenase-2, and interleukin-6).	Diosmin	47-54	interleukin 6	Rattus norvegicus	174-187